How this nonprofit aims to spur business growth in Raleigh and Whitehaven

An organization committed to closing the racial income and wealth gap in U.S. cities has started a three-year initiative to help spur growth for businesses owned by people of color in the Southeast, including in Memphis.Daniel Marshall, senior associate for Living Cities, said the organization’s Breaking Barriers to Business (B3) is a multiyear project focusing on five cities: Memphis, Atlanta, Charlotte, Miami and Nashville.In each city, Living Cities is focusing on three commercial corridors. In Memphis, those are in Raleigh, Whitehaven and Klondike-Smokey City. Marshall said the effort in Klondike-Smokey City is still in the infancy stages, while work in the other two communities is further along.Through the program, the Raleigh Community Development Corporation and RESPECT The Haven Community Development Corporation will each receive $75,000 for operational support, or $25,000 for three years, and a $50,000 grant for a physical project or program/initiative in their business corridor. The funding is provided by Living Cities through a partnership with the Truist Foundation and Main Street America for the Breaking Barriers to Business initiative. Living Cities is also working with the City of Memphis Office of Business Diversity and Compliance in providing $100,000 total in catalytic capital.“We know that this is not a large amount, but it is catalytic in a sense that we hope the organization (City of Memphis Office of Business Diversity and Compliance) can turn around and attract matching funds and much more money from governmental entities, private entities and other philanthropy,” Marshall said.Santiago Carrillo, assistant director for business ownership at Living Cities, said the work the organization is doing through Breaking Barriers to Business supports community-led efforts across the U.S. to drive systemic-level business growth and job creation in cities like Memphis that have faced disinvestment or displacement in “commercial corridors of color.”“This work helps unlock the necessary financial capital needed to build wealth within communities like Klondike-Smokey City, Whitehaven and Raleigh that strengthen the character of Memphis’ neighborhoods and drive economic growth,” Carrillo said.How RESPECT The Haven is impacting WhitehavenLiving Cities came to Memphis in late September for its national Collective Action 2024: Centering Inclusive Capital event at the Renasant Convention Center. As part of the event, Living Cities representatives and others toured Raleigh and Whitehaven and had panel discussions with business owners in each area.Jason Sharif is the founder and executive director of RESPECT The Haven CDC. The grassroots organization was founded in September 2021 to serve the predominantly Black disinvested and underserved community of Whitehaven.Sharif grew up in Whitehaven. After moving away, he came back home in 2019 to help take care of his elderly grandfather. However, when he saw how things had gone down in Whitehaven, he decided to establish RESPECT The Haven CDC to assist and coordinate with community stakeholders in helping with revitalization of the area.RESPECT The Haven CDC has a RESPECT Black Business Initiative through which it supports and promotes Black-owned businesses. This initiative led to it getting connected with Living Cities and being part of the Breaking Barriers to Business project.MEMPHIS BUSINESS NEWS:Epicenter names Anthony Young as its new president and CEOSharif said RESPECT The Haven is putting together a “business council” of about 10 Black-owned businesses to help come up with an idea for a project to put the $50,000 toward. The goal is to have an idea by the end of the year and to start the project in 2025.Sharif noted that the more capital that can be put into small Black-owned businesses in Whitehaven, the more barriers that can be eliminated that hinder their growth.”It just puts them in a better chance to be more sustainable,” he said. “We’re really hoping once we come up with our project to take that $50,000 and really leverage it to shop it around to other banks to try get those to match that money as well. Hopefully, the goal is to grow that $50,000 seed money into $500,000, if we can get nine to 10 other banks to match it. It would be a huge economic investment in the community.”‘Whitehaven is really the tale of two cities’Whitehaven is a notable and historic community in Memphis that includes many well-known landmarks including Graceland, Methodist South Hospital and Southwest Tennessee Community College’s Whitehaven Center, along with dozens of neighborhoods with a mix of working-class folks, middle-income residents and the affluent. The community’s 38,000 population is 93% Black.Although the neighborhood still has a solid retail-and-service core, that retail presence is a shadow of the Whitehaven of 20 years ago. Some residents say they drive a few miles to Southaven, across the state line, to get some basics they would prefer to buy in Whitehaven. The area has great potential, however, and is filled with residents who are committed to making Whitehaven a community of choice.“I tell people all the time Whitehaven is really the tale of two cities in Memphis,” Sharif said. “On one side, we have the highest Black median income, the most Black-owned businesses, the most registered Black voters and the most Black homeowners. We are a solid middle-class neighborhood, but at the same time we have our challenges. We have 30% poverty and we have crime. …”We talk about how we spend so much in Mississippi and send all of our money down to Southaven and Goodman Road. Not only are we taking money out of the neighborhood, but we are taking money out of the city and state.”Sharif also noted residents moving to DeSoto County among the challenges Whitehaven faces.How Raleigh CDC is looking to drive economic growthRonald Meredith has been executive director for Raleigh CDC for a little more than a year. Dedicated to spurring economic and business growth in the area, the Raleigh CDC has long been a staple in the community, having been established in 2002.Among the organization’s focus areas are job creation and the creation, development and expansion of small businesses. Meredith is a small business owner himself. He owns and serves as president of The Financial Center, an insurance agency in Cordova. He noted the heart of any community is small or family-owned businesses.“The Raleigh CDC through Living Cities, we’re focusing on how can we create economic opportunity for the small businesses we got,” Meredith said. “Everybody has heard the horror stories or the work stories that we can’t get this or we can’t get that. We’re saying, ‘How can we bring these pain points together?’ Living Cities has helped us in creating the access to make certain we can help solve some of these problems.”Meredith said the organization is still coming up with a project idea for the $50,000, but whatever it is will likely assist 25 to 30 small businesses in the Raleigh community.MEMPHIS SUCCESS STORIES:How this ‘kid from Raleigh’ became a star on Memphis’ food scene and what’s next for him“We’re still developing and coming up with some concepts of what we would like to see and the objective is getting each one of those businesses to the point where they can hire with whatever assistance we offer,” Meredith said.“If we can create strong small businesses and give strong small businesses an opportunity to survive, then they in turn can pay a living wage. If they can pay a living wage, then that’s going to help the family. If that helps the family, then that’s helping the community at large and creates stable neighborhoods, families and business community.”Signs of growth in Raleigh, from banks to new homesMeredith highlighted some of the economic activity happening in the area that some may not be aware of. He also noted how Raleigh is being impacted by the more than $1 billion development happening from a nearby Memphis suburb.Meredith said more notable financial institutions have relocated or looking to come to Raleigh. He noted Pinnacle Bank has plans to move into Raleigh, while Chase Bank recently opened a branch as well as Patriot Bank and Truist Bank.”Raleigh is changing before your very eyes,” he said. “With so much development happening in the Millington area that is close enough to Raleigh and is spilling over to Raleigh. We have banks that are moving to Raleigh. I been around long enough that if you see a bank moving into an area, then something is happening.”And Meredith is seeing more that just banks move to Raleigh. He noted the public-private partnership between Raleigh and the City of Memphis has led to the completion of an amphitheater at Raleigh Springs Civic Center, the former site of the Raleigh Springs Mall. He said the amphitheater should be able to seat 75 to 100 people when it opens. The city is currently putting the finishing touches on the amphitheater, with the Raleigh CDC planning to hold a ribbon-cutting ceremony to present the amphitheater to the community in early 2025, according to Meredith.Meredith also said the Raleigh CDC has plans to have the first on-site food truck park along with a permanent farmers market at the Raleigh Springs Civic Center. The farmers market/food truck park will resemble a park-like setting that will allow the residents to enjoy food in family-type atmosphere at little or no cost, according to Meredith. He noted the food truck park is scheduled to break ground in spring 2025 and is expected to be completed in June.”We are hoping to get as much support for the venture as possible,” Meredith said. “The hope from the CDC is that this will be well received by the community.”Meredith also pointed to new housing construction. He had a meeting with a developer in September who wants to build 170 new houses, while more than 100 new homes are currently being built on James Road. Meredith noted another new development of 92 single-family, three- and four-bedroom homes being developed by Lyons Realty Group LLC are planned to be built in the Tyler Hills Neighborhood in Raleigh.“One of the main things is price of land is affordable,” he said. “(Raleigh) has a strong political commitment from the (Memphis) City Council, (Shelby) County Commission and state representatives. The area is very well represented politically and the people (of Raleigh) care about the area. So, there is a lot going on in Raleigh, and the area is kind of like Whitehaven.”It’s a stable area and it’s not a lot of fluctuation and most of the homeowners have been there for awhile. It’s not a transient community, so I think it’s part of the reason why people are starting to give Raleigh a different look.”Corey Davis is the Collierville and Germantown reporter with The Commercial Appeal. He can be reached at [email protected] or 901-293-1610.

St. Petersburg State University scientists have found out how genes transmit information in a chicken

AK&M 20 November 2024 12:59

Biologists of St. Petersburg‑St. Petersburg State University, together with Skoltech, conducted a study of lamp brush-type chromosomes in chicken oocytes. They found out exactly how the genome of this animal transmits information, as well as how the work of genes affects the structure of chromosomes.

Scientists from the laboratory of the structure and dynamics of the cell nucleus conducted an important study that helped to learn more about how genes work on chromosomes in domestic chicken. The study was supported by the Russian Science Foundation (RNF), and the complex part of the data analysis was performed by a specialist from the Skoltech Genomic Center.

The genome of the chicken, as one of the most common animals in the world, is well studied. Lamp brush—type chromosomes are unique structures that form in the eggs (oocytes) of all vertebrates, with the exception of mammals. They are named so for its characteristic shape, resembling brushes for cleaning the glasses of kerosene lamps or test tubes, where the central axis is surrounded by many loops called lateral loops. They produce a lot of RNA at a very high rate, which makes them an excellent object for studying how genes are activated and how information is transmitted in cells as a whole.

We have completed a large, multi-component work on the study of giant chromosomes such as chicken lamp brushes. We took chicken oocytes at different stages of development and carefully extracted the nuclei from them using special tools. Then RNA was isolated from the nuclei of oocytes and from the remaining cytoplasm. This made it possible for the first time to see how and how certain genes work on chromosomes such as lamp brushes of birds.

Associate Professor of the Department of Cytology of St. Petersburg State University Alla Krasikova

So they found out that genes working on chromosomes like lamp brushes are necessary for the normal functioning of the cell. In addition, this high gene activity is important in order to transfer a large amount of information (maternal RNA) to a new organism. Another interesting discovery: it turned out that the active work of genes affects the very structure of chromosomes. And the most amazing thing is that the processes of gene activation in chickens turned out to be similar to those that occur in other cells. But due to their large size, lamp brush-type chromosomes are ideal for studying these mechanisms.

In addition, for the first time, scientists have collected detailed information about the work of small gene regulators (miRNAs) in chicken eggs. Small gene regulators, such as miRNAs (microRNAs), play an important role in controlling the work of genes. They act as “switches” and “switches”, helping to control which genes will be active at a particular time and in what quantities. In addition, it turned out that other short regulatory RNAs (piRNAs) control certain sections of DNA in the chicken genome, where there are repeating fragments.

The work was performed in the laboratory of the structure and dynamics of the cell nucleus of St. Petersburg State University with the participation of the Center for Collective Use in the field of Genomics of Skoltech.

These discoveries help scientists better understand how hereditary information is passed from one generation to another. This is an important step forward in the study of genetics and molecular biology.

The work was supported by the RNF grant “Topologically associated chromatin domains and A/B compartments in the chicken genome: identification and visualization using HiC technology and ultra‑high resolution microscopy”. It should be noted that St.‑St. Petersburg University is the leader in the number of RNF grants: in 2022, St. Petersburg State University scientists received 112 grants, which is 5.5% of the total number of winning projects and the largest number of grants for one organization. In 2023, the University retained its leadership in this RNF competition: St. Petersburg State University scientists received 70 grants, which is 5% of the total number of winning projects.
Please note that this press release is based on materials provided by the company. AK&M Information Agency shall not be held liable for its contents, nor for the legal and other consequences of its publication.

St. Petersburg State University scientists have found out how genes transmit information in a chicken

AK&M 20 November 2024 12:59

Biologists of St. Petersburg‑St. Petersburg State University, together with Skoltech, conducted a study of lamp brush-type chromosomes in chicken oocytes. They found out exactly how the genome of this animal transmits information, as well as how the work of genes affects the structure of chromosomes.

Scientists from the laboratory of the structure and dynamics of the cell nucleus conducted an important study that helped to learn more about how genes work on chromosomes in domestic chicken. The study was supported by the Russian Science Foundation (RNF), and the complex part of the data analysis was performed by a specialist from the Skoltech Genomic Center.

The genome of the chicken, as one of the most common animals in the world, is well studied. Lamp brush—type chromosomes are unique structures that form in the eggs (oocytes) of all vertebrates, with the exception of mammals. They are named so for its characteristic shape, resembling brushes for cleaning the glasses of kerosene lamps or test tubes, where the central axis is surrounded by many loops called lateral loops. They produce a lot of RNA at a very high rate, which makes them an excellent object for studying how genes are activated and how information is transmitted in cells as a whole.

We have completed a large, multi-component work on the study of giant chromosomes such as chicken lamp brushes. We took chicken oocytes at different stages of development and carefully extracted the nuclei from them using special tools. Then RNA was isolated from the nuclei of oocytes and from the remaining cytoplasm. This made it possible for the first time to see how and how certain genes work on chromosomes such as lamp brushes of birds.

Associate Professor of the Department of Cytology of St. Petersburg State University Alla Krasikova

So they found out that genes working on chromosomes like lamp brushes are necessary for the normal functioning of the cell. In addition, this high gene activity is important in order to transfer a large amount of information (maternal RNA) to a new organism. Another interesting discovery: it turned out that the active work of genes affects the very structure of chromosomes. And the most amazing thing is that the processes of gene activation in chickens turned out to be similar to those that occur in other cells. But due to their large size, lamp brush-type chromosomes are ideal for studying these mechanisms.

In addition, for the first time, scientists have collected detailed information about the work of small gene regulators (miRNAs) in chicken eggs. Small gene regulators, such as miRNAs (microRNAs), play an important role in controlling the work of genes. They act as “switches” and “switches”, helping to control which genes will be active at a particular time and in what quantities. In addition, it turned out that other short regulatory RNAs (piRNAs) control certain sections of DNA in the chicken genome, where there are repeating fragments.

The work was performed in the laboratory of the structure and dynamics of the cell nucleus of St. Petersburg State University with the participation of the Center for Collective Use in the field of Genomics of Skoltech.

These discoveries help scientists better understand how hereditary information is passed from one generation to another. This is an important step forward in the study of genetics and molecular biology.

The work was supported by the RNF grant “Topologically associated chromatin domains and A/B compartments in the chicken genome: identification and visualization using HiC technology and ultra‑high resolution microscopy”. It should be noted that St.‑St. Petersburg University is the leader in the number of RNF grants: in 2022, St. Petersburg State University scientists received 112 grants, which is 5.5% of the total number of winning projects and the largest number of grants for one organization. In 2023, the University retained its leadership in this RNF competition: St. Petersburg State University scientists received 70 grants, which is 5% of the total number of winning projects.
Please note that this press release is based on materials provided by the company. AK&M Information Agency shall not be held liable for its contents, nor for the legal and other consequences of its publication.

Belgorod scientists have created a new type of protective reflective coatings

AK&M 20 November 2024 14:04

Belgorod State Technical University (BSTU) named after Shukhov has developed and patented a new method for obtaining protective and decorative coatings with increased reflective ability. Unlike existing analogues, their production does not require expensive raw materials or complex equipment.

To apply the coating, the scientists used an air jet of a compressor, which simultaneously sprays glass beads on the surface of the product and cools the silicate melt, thereby reducing stresses in the coating and substrate and increasing the adhesion strength of the coating to the substrate. This has a positive effect on the strength properties.

“With the help of the developed technology for processing glass beads, we create thin coatings with high strength characteristics,” said Diana Bondarenko, one of the authors of the development, Associate professor of the Department of Materials Science and Technology of Materials at BSTU named after Shukhov.

Due to the fact that the coating consists of glass beads, the coating has a high reflective ability. The developed method opens up new opportunities for creating original and functional architectural solutions. A durable reflective coating can also be used in road construction to improve traffic safety.

The financing was carried out within the framework of the federal target program with the support of the Ministry of Education and Science of the Russian Federation.
Please note that this press release is based on materials provided by the company. AK&M Information Agency shall not be held liable for its contents, nor for the legal and other consequences of its publication.

Belgorod scientists have created a new type of protective reflective coatings

AK&M 20 November 2024 14:04

Belgorod State Technical University (BSTU) named after Shukhov has developed and patented a new method for obtaining protective and decorative coatings with increased reflective ability. Unlike existing analogues, their production does not require expensive raw materials or complex equipment.

To apply the coating, the scientists used an air jet of a compressor, which simultaneously sprays glass beads on the surface of the product and cools the silicate melt, thereby reducing stresses in the coating and substrate and increasing the adhesion strength of the coating to the substrate. This has a positive effect on the strength properties.

“With the help of the developed technology for processing glass beads, we create thin coatings with high strength characteristics,” said Diana Bondarenko, one of the authors of the development, Associate professor of the Department of Materials Science and Technology of Materials at BSTU named after Shukhov.

Due to the fact that the coating consists of glass beads, the coating has a high reflective ability. The developed method opens up new opportunities for creating original and functional architectural solutions. A durable reflective coating can also be used in road construction to improve traffic safety.

The financing was carried out within the framework of the federal target program with the support of the Ministry of Education and Science of the Russian Federation.
Please note that this press release is based on materials provided by the company. AK&M Information Agency shall not be held liable for its contents, nor for the legal and other consequences of its publication.

Scientists report airborne bacteria found in garbage may age our blood vessels  

It is well known that air pollution can have severe effects on heart health. In particular, any particles smaller than 2.5 microns — 20 times thinner than a single strand of hair — have the ability to enter the bloodstream through the lungs, increasing the risk of heart attack and stroke.

A new study has revealed how a lesser known form of pollution can accelerate the aging of cardiovascular tissue. This type of air pollution, known as bioaerosol, contains microscopic organisms, such as bacteria, viruses, fungal spores, and pollen, as well as small particles, and is commonly found in garbage stations that collect household waste.

“Urban garbage collection stations are essential in daily life; their enclosed environments and large amounts of kitchen waste promote the growth of microorganisms, posing significant health risks to residents,” said Caiwen Ou from Southern Medical University in China.

“This study demonstrates that high concentrations of pathogenic bioaerosols exist in household garbage collection station environments. Additionally, chronic exposure to these high concentrations can accelerate vascular aging in mice.”

The study, published in Advanced Science, is the first to show that the microbes found in bioaerosols can accelerate the aging of blood vessels, compounding the already known health risks caused by air pollution.

Ou and colleagues also identified how this happens at a molecular level, a discovery that could pave the way to developing treatments against the long-term effects of this type of pollution. They hope that their research will be a wakeup call for governments and regulatory agencies to start implementing stricter policies aimed at protecting people who are chronically exposed to bioaerosols, such as specialized workers and neighbors who live close to garbage collection stations, from these health hazards. 

Investigating bioaerosols

To learn more about the effects of bioaerosols on human health, the scientists first looked at historical data from over 8,000 people 45 years or older who took part in a study looking at the overall health of Chinese citizens all over the country.

The participants were divided into four groups based on the levels of exposure of their households to air pollution and bioaerosols. Those in the group with the highest exposure to this type of pollution (96 μg/m3 on average) had a 35% higher risk of reporting strokes, heart attacks, and heart failure after two years compared to the people with the lowest levels of exposure (36 μg/m3 on average).

In order to correct for any outside factors, the scientists adjusted the data according to criteria such as age, gender, smoking status, and established disease, among others. Even after this, they found a statistically significant correlation between exposure to bioaerosols and cardiovascular events.

The researchers then analyzed samples of bioaerosols from a household garbage transfer station in Guangzhou, China. They found that the concentration of bioaerosols in household garbage stations was significantly higher than that of stations located in office buildings and schools, and identified numerous types of bacteria present in the sample.

“The analysis of the samples indicated that a majority of the bioaerosol particles found in garbage stations were small enough to be inhaled,” explained Ou. “Their transmission potential is extensive.”

While these preliminary results were concerning, the researchers still need to establish a causative link between the elevated levels of bioaerosols and a higher risk of strokes and heart attacks. To further investigate this link, they looked at the effects that pathogens found in bioaerosols can have in our health.

Aging blood vessels

The researchers selected a strain of Staphylococcus caprae from the garbage station samples to further investigate its effects on cardiovascular health. This bacterium can naturally be found on our skin, where it is usually harmless, but it is also known to cause severe infections when it manages to make its way into the bloodstream.

When exposing the cells that make up our blood vessels, called endothelial cells, to bioaerosols containing this bacterium, they showed signs of accelerated aging compared to healthy cells. This effect was stronger at higher concentrations of S. caprae, however, the experiments did not include an exact comparison of the concentrations typically found in bioaerosols.

The researchers identified a specific protein that was activated in the presence of the bioaerosols, called NK-κB. This small protein is involved in controlling the immune system to protect the body against external threats, however, when activated in excess, it is linked to inflammation, autoimmune disease, and cancer. 

In human cells and in mice, the scientists found that bioaerosols activated this protein, triggering inflammation, which in turn activated genes linked to aging — this was determined by measuring the output of genes known to play a role in cellular aging. In addition, mice exposed to bioaerosols developed thicker and less elastic arteries, which are common signs of vascular aging. 

This discovery not only highlights the additional precautions needed when dealing with bioaerosols, but also that the more we know about them, the better situated we are to develop medicines and preventative therapies against the harmful effects of bioaerosols.

“Developing vaccines or immunotherapies targeting specific biological aerosol components may be able to prevent or mitigate their adverse effects on human health,” said Ou. “However, the development and application of these treatment measures require further scientific research and clinical trials to verify safety and effectiveness.”

Next, the scientists aim to conduct further research into how bioaerosols cause inflammation and vascular aging at the molecular level, as well as study how people of different gender, age, and health status respond to bioaerosols to identify potential protective measures.

“We believe that this research can remind governments and regulatory agencies to strengthen monitoring and control of bioaerosols in the air, especially in areas with severe (…) pollution,” said Ou. These may involve stricter emission standards, further health monitoring and additional protective measures for workers in high-risk environments.  

“Our objective is to translate our findings into effective public health policies and interventions that reduce the impact of bioaerosols on community health,” Ou concluded.

Reference: Guoxia Zhang, Feiran Zhou, Caiwen Ou, et al., Chronic Exposure to Bioaerosols in PM2.5 from Garbage Stations Accelerates Vascular Aging via the NF-κB/NLRP3 Pathway, Advanced Science (2024). DOI: 10.1002/advs.202404142

Publicis Groupe ME partners with Dubai Business Women Council

A workshop by Publicis Groupe Middle East and Dubai Business Women Council.
Publicis Groupe Middle East has partnered with the Dubai Business Women Council (DBWC) to launch a series of tailored workshops aimed at empowering women-led micro, small, and medium-sized enterprises (MSMEs) in Dubai.
The sessions, designed to provide practical marketing and communications expertise, aim to signify a step towards fostering a more inclusive business landscape. Through this partnership, DWBC members will gain access to some of the same strategic insights that drive success for both global and regional leading brands.
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