Why Is Small Business Administration Lending Suddenly Surging?

Share to FacebookShare to TwitterShare to LinkedinSmall Business Administration backed lending is off to a near-record start in 2025.

The SBA approved $8.8 billion in 7(a) loans during the first quarter of the federal fiscal year (which started on October 1), making it the second-fastest start since 1991, when the agency began tracking data. The number is up 38% from the first quarter of 2024. The last time the program saw such a strong start was 2011, following the Small Business Jobs Act of 2010, which raised from $2 million to $5 million the cap on the amount an individual business owner could borrow.

The 7(a) program has long been a favorite among business buyers. Established in 1953, it allows borrowers to secure loans for up to $5 million, with favorable terms that include low down payments and extended repayment schedules. The loans are especially popular for funding acquisitions of existing businesses, thanks to their government-backed guarantees that reduce risk for lenders.

Mark Edler, the founder of Builders.CPA, an accounting firm that caters to small business buyers, says there are a few reasons for the surge in SBA loan volumes.

“There’s a constant flow of people who are really looking to acquire a business because they’re looking to change their life and lifestyle,” he says. And, unlike big corporations, where M&A activity rises and falls with interest rates, aspiring entrepreneurs buying businesses don’t let high rates stand in the way of their plans.
Edler also points to recent SBA rule changes that have made dealmaking easier. In May 2023, the SBA began allowing borrowers to take out multiple 7(a) loans, offering nearly unlimited funding as long as the acquisitions are in different industries. A December 2024 update went further, permitting buyers to use agency-backed loans while offering the seller equity in the new business—an option previously prohibited.

Stephen Speer, founder of eCommerce Lending, an online business acquisition advisor, sees more tailwinds driving the market. Among them, Baby Boomers are providing a steady supply of established and profitable small businesses for sale, as they look to exit and retire. Many of these decades-old businesses have rightfully gained buyer confidence by proving their resilience during the COVID-19 epidemic.
Add it all up, and Speer says “the record pace of SBA business acquisitions will likely continue through 2025.”
But Jerry Freedman, a principal at Freedom Business Financing, believes acquisitions aren’t what’s fueling the boom. His analysis of the SBA data and talks with lenders lead him to believe that much of the volume is for small loans and SBA Express lines of credit. The SBA’s Small Loans and Express Lines of Credit programs are subsets of the 7(a) loan program, designed to provide faster and more accessible funding. Small Loans offer financing up to $500,000, while Express Lines provide quick access to revolving credit, both backed by the SBA to reduce lender risk.
“While I get the excitement regarding business acquisitions and the ‘Silver Tsunami’—and I am excited too and love helping searchers finance their dream acquisitions, I don’t believe the volume is being driven by acquisitions,” Freedman says.
Ray Drew, managing director of Winston-Salem, North Carolina-based Truliant Federal Credit Union and host of The Art of SBA Lending podcast, notes that while loan volume is up, the average loan size continues to come down. He says that’s in part because banks and credit unions are stepping in to provide smaller loans to businesses. Previously, he says, that space was occupied by fintechs that were charging “an arm and a leg” which could send borrowers into a “death spiral.”
Miami-based Newtek Bank led lenders in the first quarter, approving $738 million in loans. It was also the top lender for fiscal 2024, with $2.1 billion approved. Live Oak Banking Company, based in Wilmington, N.C., followed with $564 million in approvals, while The Huntington National Bank in Columbus, Ohio, came in third with $423 million. Together, the top three accounted for 20% of total loan volume.
“Up until a few years ago, most SBA lenders stayed away from smaller loans,” Drew says. “But through the use of technology, lenders have benefitted from efficiencies which have made the small loan game more economical.”

Louisville Fire issues violation to business operating as overnight shelter during winter storms

A south Louisville business operating as an overnight shelter has been issued a violation by the fire department.The StrEatery, which is located in the Beechmont neighborhood, has been using its space as an overnight shelter for the homeless in the city as frigid temperatures and winter weather stick around. The Louisville Fire Department said it issued a notice to the business on Thursday to suspend its overnight operations until additional permits and approvals are obtained from Metro Codes and Regulations.”For residential or shelter use, a change of occupancy permit must be applied for through Metro Codes & Regulations, even for temporary use as Building and Fire codes have specific requirements based on the use of the building,” Louisville Fire officials said in a statement. In light of this, the South End Street Angels said they had to turn away more than 10 people.”It’s disappointing, and we just told them they can’t stay,” said Amanda Mills with the South End Street Angels.The people staying there said they don’t have many other options. The South End Street Angels are encouraging anyone who needs a place to stay to use the city’s White Flag shelters.

LOUISVILLE, Ky. — A south Louisville business operating as an overnight shelter has been issued a violation by the fire department.The StrEatery, which is located in the Beechmont neighborhood, has been using its space as an overnight shelter for the homeless in the city as frigid temperatures and winter weather stick around.

Trump Administration 2.0 – Tech Transactions Update

The incoming Trump administration is expected to make several policy changes likely to impact tech transactions. President-elect Donald Trump has promised to reduce regulation and cut federal bureaucracy, which he says have suppressed innovation, increased the cost of goods, and caused jobs to shift oversees. He has touted an “America First” focus on domestic manufacturing and supply chain independence, particularly of semiconductor and AI-related technology. The first Trump administration’s track record also offers some predictive insights, though we expect some differences from his first term. The overall effect of these changes could reshape the landscape of tech transactions during the next four years.

Targeting Regulation

In his first term, Trump pledged that for every new regulation issued, two federal regulations would be permanently removed. In his 2020 campaign, he stated that his administration exceeded that goal by removing eight regulations for every issued regulation, and in the most recent campaign pledged to remove ten for every issued regulation. While few believe Trump can meet this 10-to-1 pledge, many believe, and we agree, that Trump will be slower to adopt new regulations and will repeal Executive Orders issued by President Joe Biden.

A. Approach to AI Regulation

Trump pledged to repeal Biden’s Executive Order 14110, which set a regulatory framework with guardrails on AI development and use. Trump asserted that Biden’s regulations threaten free speech and hinder AI innovation. As part of his next administration’s strategy, Trump announced the appointment of David O. Sacks as the White House A.I. & Crypto Czar. Sacks is expected to play a key role in shaping Trump’s AI policy. While Biden’s AI Executive Orders focused on addressing potential risks of bias in the use of AI, such as in hiring and law enforcement, Trump is instead focused on bias in content moderation, stating that Sacks will “steer us away from Big Tech bias and censorship.” Trump is expected to discard proposed government AI controls addressing diversity and equity, but maintain and potentially strengthen export controls on AI technology and advanced semiconductor chips going to China, continuing the trend of leveraging AI to enhance U.S. national security.

Trump views AI as essential to U.S. competitiveness, stating,

“We have to be at the forefront. It’s going to happen. And if it’s going to happen, we have to take the lead over China.”

The Trump administration’s pro-AI development policies, combined with export controls on AI technologies, are likely to create both opportunities and challenges in technology transactions. Policies aimed at establishing U.S. leadership in AI could spur licensing agreements, joint ventures, and collaborations focused on AI innovation. With less AI regulation in the U.S., companies involved in AI development may see increased opportunities for funding and partnerships, driving activity in the tech transactions space. Regardless, AI regulation outside the U.S. is full speed ahead. For companies operating in Europe, the EU AI Act is already in effect, with enforcement phasing in over the next two years.

It should be noted that AI-related technology transactions include risks beyond regulation. For example, legal counsel will need to ensure proper ownership or license rights and consents for training data, uses of IP and data in AI models and any generated output. For buyers and investors, we also recommend adding robust AI-specific representations and warranties into AI technology transaction agreements to address these risks.

B. Scrutiny of Technology Transactions

Policy and personnel changes at the Federal Trade Commission (“FTC”) and Department of Justice (“DOJ”), the U.S.’s primary antitrust enforcers, are also likely to affect the ecosystem for tech transactions. Biden’s FTC challenged several high-profile mergers, including Microsoft’s acquisition of Activision Blizzard, and launched an antitrust investigation into Microsoft’s cloud computing, software licensing, cybersecurity, and AI businesses. Trump is expected to exercise less power in blocking mergers, particularly outside of the health and tech sectors, but Trump’s announcement of Andrew Ferguson as the FTC chair leaves some ambiguity. Ferguson has been vocal about his skepticism toward big tech, particularly its control over free speech and market power. While Trump’s leadership may reduce regulatory barriers for certain mergers, it could give heightened scrutiny to others, such as for big pharmaceutical companies, social media, and other media-focused technology transactions. Trump has also tapped Elon Musk and Vivek Ramaswamy to head a non-agency advisory board, named the Department of Government Efficiency (”DOGE“), to ”dismantle Government Bureaucracy, slash excess regulations, cut wasteful expenditures and restructure Federal agencies.” While details as to the proposed cuts are limited, the Wall Street Journal has reported that unnamed sources identified the FTC and DOJ as being subject to possible cuts.

President Trump has been critical of the CHIPS Act of 2022 (the “CHIPS Act”), which received bipartisan support when adopted in 2022. The CHIPS Act set aside $52.7 billion for chip research, manufacturing and workforce development in the U.S. In one high profile example, the Act incentivized Taiwan Semiconductor Manufacturing Company (TSMC) to increase investment in a large semiconductor plant in Arizona. Trump, however, has criticized the CHIPS Act as a wasteful giveaway of federal funds, arguing that tariffs (or the threat of tariffs) could better incentivize semiconductor manufacturing in the U.S. Trump also claims that Taiwan “took almost 100%” of the semiconductor industry from the U.S. and in return has not paid its fair share towards its military defense. In addition, Trump may take steps to strengthen enforcement under the Buy American Act of 1933 (“BAA”), which mandates the use of US-manufactured supplies and construction materials on federal contracts. We expect more scrutiny of technology transactions that involve manufacturing of critical technology outside the U.S. or that involve government funds going to entities outside the U.S. Buyers and investors might do well to conduct robust risk assessments and contingency planning, especially for transactions involving high-profile or politically sensitive businesses or non-U.S. stakeholders.

Regardless of federal policy or cuts in the budgets of government enforcement agencies, we expect states and foreign jurisdictions will continue enacting new laws governing AI and data privacy, creating a patchwork of compliance requirements for companies operating across multiple jurisdictions. Even if a comprehensive federal framework were enacted that preempts these state laws, which seems unlikely given Trump’s 10-to-1 pledge to reduce regulation, legal counsel for global businesses must remain vigilant in monitoring legal developments outside the U.S. and tailoring transaction agreements to address evolving global AI and data privacy obligations.

C. Regulation of Cybersecurity

We do not expect the second Trump administration to make private-sector cybersecurity regulation a priority. Instead, voluntary industry efforts and cooperation will likely be encouraged. Despite this anticipated approach, private investment in cybersecurity measures will likely continue to increase. Cyberattacks, particularly ransomware, increasingly target business operations throughout the world. The new Trump administration is expected to focus more heavily on cybersecurity in the national security space, with Trump’s platform emphasizing the protection of critical infrastructure from malicious cyber attackers as a national priority.

Trump previously established the Cybersecurity and Infrastructure Security Agency (“CISA”) in 2018 through the Cybersecurity and Infrastructure Security Agency Act. Subsequently, the Cyber Incident Reporting for Critical Infrastructure Act (“CIRCIA”), enacted on March 15, 2022, authorized CISA to develop regulations requiring critical infrastructure entities to report cyber incidents and ransom payments. These regulations aim to enhance national security and cybersecurity resilience by improving situational awareness, threat analysis, information sharing, and incident response. While CISA is expected to publish the final rule by October 2025, the incoming administration’s priorities could lead to changes in balancing private sector expectations with national security concerns.

Although the president-elect’s platform underscores the importance of cybersecurity vigilance, Trump has historically emphasized reducing regulatory burdens on businesses to promote economic growth. Critics argue that CIRCIA’s mandatory reporting requirements impose a heavy burden on private companies, particularly small and medium-sized enterprises, potentially discouraging incident reporting or collaboration with CISA. Furthermore, potential cuts from the DOGE could impact CIRCIA’s implementation. CISA has faced criticism for overstepping its mandate and becoming overly bureaucratic, making it a possible target for review and reform under the DOGE. While CISA is unlikely to be eliminated, its proposed regulations under CIRCIA may face delays or revisions as part of the incoming administration’s efforts to reduce regulatory burdens and realign federal agency priorities.

While the incoming administration’s focus on voluntary cybersecurity measures may reduce regulatory burdens on private companies, it shifts the onus of implementing cybersecurity protections onto the private sector. This creates a heightened focus on cybersecurity provisions in transaction agreements, including representations, warranties, and indemnities related to data security and increased scrutiny on a company’s data security practices during the diligence stage.

Patent Policy

During his first administration, Trump appointed Andrei Iancu as director of the U.S. Patent and Trademark Office (“USPTO”), leading to a pro-patent owner policy focused on reducing regulation, increasing patent application filings, and boosting patent issuance, particularly for U.S. filers. Companies with healthy patent portfolios tend to support higher valuations in the tech transactions space, and create opportunities for strategic transactions involving IP assets; however, more patents may lead to more overall risk of patent infringement, a risk that can be difficult to quantify during the diligence phase of a transaction. It is anticipated that Trump’s pick for USPTO director will similarly foster a patent-friendly environment.

What is less clear is how Trump’s views towards China may impact policy at the USPTO. The U.S. and China are members of the Patent Cooperation Treaty, and therefore each is required under the “national treatment principle” to not discriminate against filers from member countries and to provide imported patents the same treatment as domestic patents. It is not clear whether and how the Trump administration might try to discriminate. China is now the largest filer of patent applications globally, surpassing the U.S. in 2010; however, only a small percentage are filed outside China. Nevertheless, the number of US-granted patents originating in China has been growing steadily.

Policy on IP Infringement and Theft

Trump’s appointment of Peter Navarro as senior adviser for trade and manufacturing signals a renewed commitment to his campaign promise of leveraging tariffs against China. During Trump’s first term, Navarro advocated for aggressive trade measures to counter unfair technology transfer and IP theft by the Chinese government, ultimately leading to tariffs and a trade war with China. Navarro’s elevated role in the second Trump administration underscores the importance of tariffs as a tool to address IP theft and protect American interests in international trade.

In addition, Trump has named Jamieson Greer as the United States Trade Representative (“USTR”). Greer, who previously served as chief of staff to then-USTR Robert Lighthizer during Trump’s first term, is expected to play a central role in designing and implementing tariffs to combat unfair international trade practices, particularly those harming U.S. IP. During the first Trump administration, the USTR conducted an investigation under Section 301 of the Trade Act of 1974, at Trump’s direction, to assess the impact of Chinese trade practices on U.S. IP rights and technology development. The resulting 2018 report detailed extensive unfair practices, prompting Trump to impose tariffs and escalate a trade war with China. Greer was instrumental in advising on these tariffs, and his appointment signals a likely continuation of aggressive trade policies, with the potential for further tariffs following the playbook he helped craft.

The incoming administration’s focus on addressing IP theft through tariffs and other aggressive trade measures is expected to have significant implications for international technology transactions. Companies engaged in cross-border licensing agreements or supply chain arrangements may need to reevaluate their contracts to account for new tariff structures or trade restrictions.

Additionally, the emphasis on tariffs as a tool to counter IP theft underscores the importance of robust IP protection. Legal counsel should anticipate increased demand for renegotiating cross-border agreements and structuring deals that account for trade policy changes.

Other Policy Changes

Trump also hinted at other policy changes that could significantly impact the tech transactions space, including support for nuclear energy, space exploration, satellite defense technology, adoption of autonomous vehicles, cryptocurrency and broader applications of blockchain technology. We recommend keeping a close eye on developments in these areas.

Legal counsel will need to ensure that tech deal structures are resilient to potential changes in the legal landscape not only under the Trump administration, but also the administrations that follow, which could take a different approach in each of the areas discussed.

Google becomes latest tech giant to send Trump money

If you need some, uh, different bad news to break up your already bad news day, here’s some: Google just donated $1 million to Trump’s inaugural fund, per The Washington Post. (We can’t use Bing anymore either, because that’s an AI wasteland. Apparently there’s an alternative engine called Swisscows.com? That one sounds nice.)
If you don’t know what the hell an inaugural fund even is, it’s pretty much exactly what it sounds like. Trump is trying to throw the biggest party in D.C. on January 20, and the search engine’s CEO, Sundar Pichai, and founder, Sergey Brin, want a spot at the table. They already had one at Mar-a-Lago; the two men dined with the president-elect last month, despite the fact that Brin was supposedly “deeply offended” by Trump’s election the first time around (per WP). Meta, Apple, and OpenAI are also vying for spots on the list with $1 million donated apiece. 

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The potential motivation behind Google’s decision is so simple it almost hurts. In addition to the basic sucking up that everyone else seems to be doing right now, Biden’s Justice Department is currently seeking to break up the company under anti-trust laws. Under Trump, that might not happen—especially if Google’s parent company, Alphabet, is on his good side. 
Big tech isn’t the only industry pouring their resources into Trump’s inauguration right now. Per The New York Times, the fund has raised over $170 million for the president-elect’s swearing in, which will, coincidentally, be livestreamed on Google. If you need some schadenfreude on this brutal news day, that means that some of those donors have been placed on a waitlist to attend the ceremony, or may not get their precious V.I.P. tickets at all. Silver linings, maybe?

More from A.V. Club

7 Must-Read Historical Fiction Books About America’s First Families

While you could fill a library with biographies, autobiographies and other nonfiction books about U.S. presidents, the stories of their wives and families often get pushed aside. However, with presidential historical fiction books, you can glimpse some of history’s most influential first ladies and immediate family members. Filled with a combination of actual events and captivating, imaginative details, these stories detail the lives of powerful women who may get overlooked. 
From exploring Mary Todd Lincoln’s secrets to wondering what would have happened if Hilary Rodham hadn’t married Bill Clinton, these enticing stories will surely catch your interest. We compiled our favorite presidential historical fiction books, which bring intimate and hidden moments to life. Keep scrolling for all our recommendations. Happy Reading!

Berkley
Eleanor Roosevelt was an outspoken First Lady who fought for civil and women’s rights. This novel explores her decades-long friendship with W Mary McLeod Bethune—an activist, educator and daughter of formerly enslaved parents. The pair shared their secrets and dreams over the course of their adult lives, the friendship becoming something they both relied on. 
What readers are saying: “This book provided details on historical events that I had no awareness of. Written impeccably with great character development and fantastic historical factual events of the time. I highly recommend this novel. I truly enjoyed it from start to finish. Amazing women who shaped our country.”

William Morrow Paperbacks
From a young age, Martha “Patsy” Jefferson Randolph understood that even though her father, Thomas Jefferson, loved his family, his devotion to his country ran deeper. As his eldest daughter, Patsy becomes his protector and constant companion after her mother’s death and she travels with him when he becomes the American minister to France. While in Paris, Patsy learns of her father’s troubling connection with Sally Hemmings, a slave girl who’s also her age, and falls in love with William Short, a staunch abolitionist and determined diplomat. Stuck between love and duty to family, she questions whether she can simultaneously be William’s wife and a devoted daughter. 
What readers are saying: “Stephanie Dray and Laura Kamoie, thank you for enlightening us all with Patsy Jefferson’s story! America’s First Daughter was an all-consuming read that kept me up several nights! By the end, I felt like I fully understood this remarkable woman’s hopes and dreams, strengths and weaknesses, and endearing compassion to those most present in her life.”

Mariner Books
Before she was Jackie Kennedy, she was Jackie Bouvier. The story follows 20-year-old Jacqueline as she embarks on her junior year abroad in Paris. Before succumbing to family pressure and expectations, she has a year to herself away from Vassar College and the high society of New York. Soon, she’s immersed in a new life and even strikes up a romance with a young writer—although her mother would never approve. But underneath the glamour, France is still haunted by the Occupation. In the aftermath of World War II, Paris became a hot spot for spies, secrets and betrayals. Stunned, Jacqueline watches the rise of communism unfold, unaware that these events will shape the rest of her life as well as her future husband’s.
What readers are saying: “This book was an absolute page-turner for me. At first, I read it as a piece of historical fiction about Jackie O, but pretty soon, I got lost in the story about this woman in 1949 Paris. Ann Mah paints a beautiful portrait of Paris, but also a very realistic one of a city and country recovering from WWII. I highly recommend this book!”

Dutton
In this historical fiction novel, New York Times bestselling author Jennifer Chiaverini unveils the private life of Mary Todd Lincoln through the eyes of her most trusted confidante and friend. Elizabeth Hobbs Keckley was born a slave, but it was her skills as a seamstress that gave her what she desired most: freedom. Those same talents also won her the friendship of Mary Todd Lincoln. Mrs. Lincoln’s Dressmaker sheds light on the relationship between the two women, beginning during the Civil War and lasting until almost the end of Mary’s days. 
What readers are saying: “If you choose one historical novel to read this year about America I recommend this one. Mrs. Lincoln’s Dressmaker is well-researched and crafted carefully, never failing to intrigue, fascinate and inform the reader about the tumultuous Civil War years when history forced dramatic changes on the nation and on individuals living during those precarious years.”

Random House Trade Paperbacks
What would have happened if Hilary Rodham hadn’t married Bill Clinton? In 1971, Hillary Rodham has a life full of opportunity. Life Magazine covered her commencement speech from Wellesley. She’s attending Yale Law School and is an activist for women’s rights. And fellow law student Bill already has his political career planned out. In our world, Hillary followed Bill to Arkansas, where she rejected his proposal multiple times but ultimately accepted and eventually became Hillary Clinton. But in this book, her story ends differently. She leaves Arkansas and blazes her own trail for the next 40 years. However, she crosses paths again and again with Bill Clinton, leaving her to question the tradeoffs involved in building a life.
What readers are saying: “Curtis Sittenfeld does an amazing job of world-building and detailing the intimate life of a narrator who never fails to sound like Hillary Rodham Clinton. Even the most outlandish parts are plausible, and the fictional take on stuff that actually did happen seems eerily right on the money. I started and finished this book in one day. I simply could not put it down. It’s evident that the author really did the work to make it both brilliant and believable.”

Penguin
Historical fiction meets murder mystery in this story from Barbara Hamilton. It’s 1773, and the colony of Massachusetts is torn between patriots who want their freedom and loyalists who support the king. At the center of it all is the president’s wife, Abigail Adams, who happens to be the leader of the Sons of Liberty, a secret organization opposing the Crown. When a murder occurs, John is immediately accused of the crime. With his reputation and the fate of the Sons of Liberty on the line, Abby must solve the case to ensure their freedom.
What readers are saying: “This is an excellent beginning to a series of mysteries featuring the inestimable Abigail Adams. Very enjoyable. I particularly enjoyed learning about daily life in 18th-century America.”

Sourcebooks Landmark
Widow Edith Bolling is in no rush to find a new husband. However, she can’t resist Woodrow Wilson’s charms; suddenly, she’s the First Lady of the United States. The role is uncomfortable for an independent woman like herself, but she’s determined to rise to the challenge. Soon, she becomes an indispensable part of her husband’s presidency, discussing policies daily and encrypting secret messages. When Woodrow’s health worsens, Edith essentially steps into the presidential role to keep her husband’s progress and reputation alive. 
What readers are saying: “I loved this fictional insight into the life of Edith Wilson. While I know we cannot know her personal thoughts and actions, this book makes me feel as if Edith Wilson herself was providing behind-the-scenes stories of our American history. It puts a human touch to a very pivotal part of our history.”

Black Voices: Lowcountry historian to release new book about South Carolina

CHARLESTON, S.C. (WCSC) – A Lowcountry historian-turned-storyteller is shedding light on cultures worlds apart and the connections between them.Damon Fordham knows the art of storytelling. It’s in his blood.“I had a father who loved to tell stories and who lived through a lot of history, and so he loved to talk about these things and I loved to listen,” Fordham says. “And then I was pretty much a bookworm as a kid. So I read a lot of things and when I would read some of the very things that my father would talk about, say World War II, the Great Depression, segregation and such, it really struck a cord that I was able to connect these things.”Fordham, an adjunct professor of history at The Citadel is writing his own stories to tell and experiences of Black communities in the Palmetto State are taking center stage. Fordham is preparing to release his new book, “Black Folk Tales and Chronicles of South Carolina.”“This book is a preservation of this wisdom, humor and knowledge of our elders of previous generations because that tradition of the elders telling stories and life lessons and all that, that largely died out within the ‘60s and ‘70s,” he says. “But see, my parents were old enough to be my grandparents, you see? So I was able to be that last generation to get a hold of that.”Damon Fordham’s book, ““Black Folk Tales and Chronicles of South Carolina,” will be released on Tuesday.(Live 5)Fordham says being born in Spartanburg, growing up in Mount Pleasant and Columbia and attending the University of South Carolina, allowed him to be able to listen and learn from the past experiences of those around him. Their stories now line the pages of his fifth book.It has been a project two years in the making.“What I would like [readers] to walk away with is exactly know that many of the ancestors in previous days went through some hard times,” he says. “But these stories reveal some of the ways that they got through those hard times and the type of ways that they used humor in order to deal with that, as well as how they used their experiences as well as mythology and folklore to give life lessons not only to the youth, but also to adults.”He says he works to find a balance between highlighting the tragedies and triumphs of Black communities.“There’s some people who concentrate on nothing but the tragedies because they feel that that will quote, ‘wake people up’ and there are some who only concentrate on the triumphs because they believe that people don’t need to hear the bad things,” he says. “If all you focus on are the tragedies, it would freeze people into hopelessness and think that nothing could be done. But if all you feel—concentrate on are the triumphs, then people will not know what to do when the tragedies come. So, what I do is a balance of these things so that when people go through tragic times, they will know from the history of these tragedies not only that they’ve been there before, but how to go about dealing with that situation.”Fordham finds a direct connection between South Carolina and the tradition of oral storytelling that he observed during his travels throughout West Africa he also hopes to bring focus to his book.“This is what kept us as people together for many years and it would be a tragedy if all of that wisdom would be forever lost—and humor—be forever lost to the graveyard,” he says.Fordham’s book will be released on Tuesday. He’s also hosting a launch event that day at Buxton Books in Downton Charleston, located at 160 King Street, at 5:30 p.m.The public is invited to attend.Copyright 2025 WCSC. All rights reserved.

University Hospitals and Case Western Reserve University Launch $250,000 Collaborative Science Pilot Awards to Propel Five Innovative Research Projects

University Hospitals (UH) and Case Western Reserve University School of Medicine have embarked on a transformative journey in medical research by launching the Collaborative Science Pilot Awards. This innovative program, designed to foster the integration of clinical and basic science expertise, has recently awarded significant funding to five research teams. This funding initiative aims to not only support but also inspire groundbreaking scientific studies that can lead to advancements in patient care and treatment methodologies. The importance of collaboration between physician-scientists and research scientists cannot be overstated, as it is often the spark that ignites impactful discoveries. The awarded teams, each selected through a rigorous peer-review process, reflect a diverse array of medical disciplines. Each team received $50,000 with a promise of additional funding contingent upon scientific progress and successful milestone achievement. This financial backing signifies a commitment from both institutions to nurture interdisciplinary research projects that might otherwise struggle to find sufficient funding. Targets include key areas of potential innovation—ranging from genetic investigations in ophthalmology to neurodegenerative disease therapeutics—underscoring the multifaceted challenges confronting contemporary medicine. One exemplary project is the creation of a comprehensive MR Fingerprinting Quantitative Neuroimaging Database. Led by experts in radiology and biomedical engineering, this initiative is set to redefine how neurological diseases are studied and diagnosed. MR Fingerprinting offers a revolutionary imaging technology that can enhance the precision of neuroimaging. By developing a substantial database, the team aims not only to facilitate hypothesis-driven research but also to establish a framework for a multi-institutional consortium. Such collaboration is critical for generating robust, validated biomarkers that could significantly improve our understanding of neurological disorders. The second innovative project focuses on early detection strategies for keratoconus, a disease characterized by thinning of the cornea that can cause profound visual impairment. The team, comprised of experts in population health and ophthalmology, plans to produce a Polygenic Risk Score that integrates genetic testing with existing diagnostic measures. This ambitious approach aims to improve early detection rates, allowing for timely intervention that can prevent serious visual loss. Their model utilizes existing biobank data combined with new cohorts from the UH Cleveland Medical Center to validate and refine these genetic biomarkers. In the realm of neurodegenerative diseases, a pivotal project seeks to understand the therapeutic effects of inhibiting a protein known as 15-PGDH in the context of Alzheimer’s disease. Research scientists are at the forefront of discovering how this protein contributes to neurodegeneration, with plans to analyze gene expression in myeloid cells. This methodology could unveil novel pathways through which pharmacological intervention could preserve cognitive function in Alzheimer’s models. The implications of such a study are profound, as they may lead to potential disease-modifying treatments, an area where there is currently significant clinical need. Another intriguing project tackles gastrointestinal (GI) symptoms in patients with Autism Spectrum Disorder (ASD). This interdisciplinary team proposes to investigate the microbiome profiles of ASD patients, particularly focusing on microbial imbalances that lead to gut issues. The hypothesis centers around the idea that probiotics can ameliorate dysbiosis and relieve the associated gastrointestinal distress. Given the complex nature of ASD, understanding how gut health interplays with neurological outcomes could offer new avenues for both nutritional and therapeutic interventions. Moreover, a research initiative focusing on malaria highlights how cutting-edge funding can fuel discoveries that are not only academic but also have the potential for significant public health impacts. This ongoing study examines the role of bradykinin in the cascade of cerebral malaria, linking genetic models to potential therapeutic developments. By targeting the kinin system, researchers aim to derive new pharmacological strategies that can accompany traditional anti-parasitic treatments, thus enhancing patient outcomes in severe malaria cases. Collaboration at such a level exemplifies the new paradigm in scientific research, where diverse expertise converges to tackle intricate health challenges. The strength of the Collaborative Science Pilot Awards lies in its foundation upon mutual goals of discovery and innovation, allowing researchers to explore uncharted territories with the backing of their institutions. By bringing together senior investigators and early-career faculty, the program ensures that knowledge transfer and mentorship are integral components of the research process. This fosters an environment where ideas can flourish, and innovative solutions can emerge to address urgent medical needs. As these projects unfold over the coming months and years, the continued evolution of the scientific landscape at University Hospitals and Case Western Reserve University will surely lead to both local and global advancements in healthcare. The rigorous evaluation protocols, coupled with the commitment to comprehensive research, form a robust framework that supports the kind of transformative science necessary for impactful clinical application. The insights gained from these interdisciplinary collaborations hold the promise to shift paradigms, redefine practice standards, and ultimately enhance health outcomes for diverse patient populations. The narrative of scientific achievement is continuously rewritten through initiatives such as the Collaborative Science Pilot Awards. The outcomes of these funded studies will not only propel the individual research initiatives but will also enrich the broader medical community. As the teams engage in their investigations, the potential to identify new diagnostic markers and therapeutic strategies will constitute a significant contribution to their respective fields. The ripple effects of these innovative studies may reshape protocols, enhance treatments, and ultimately contribute to improved public health and patient care. In conclusion, as the medical research community navigates the complexities of modern healthcare, programs like Collaborative Science Pilot Awards illuminate the path forward. They empower researchers to engage collaboratively, transcending traditional silos that often hinder progress. The synergy bred from these collaborations is essential for facing the multifaceted challenges of healthcare today, and the insights gained through these funded projects may set the stage for the next wave of scientific breakthroughs. — Subject of Research: Collaborative Science Pilot AwardsArticle Title: University Hospitals and Case Western Reserve University Propel Innovation Through Collaborative Research InitiativesNews Publication Date: Late 2024Web References: [Insert relevant URLs here]References: [Insert relevant references here]Image Credits: [Insert relevant image credits here] Keywords: Collaborative research, medical innovation, neuroimaging, keratoconus, Alzheimer’s disease, Autism Spectrum Disorder, malaria, genetic testing, microbiome, scientific collaboration.