Daily Archives: January 14, 2025

Scientists sound alarm on Bill Gates-advocated use of mosquitoes to vaccinate humans

by WorldTribune Staff, January 13, 2025 Real World NewsDr. Peter McCullough noted in a recent post to his Substack.com blog: “It seems as if the world of vaccinology has ramped up to a feverish pitch with amplified research, massive funding, and no limit to the extent in which vaccines could be injected into humans.”
That amplified research now includes human clinical trials that use mosquitoes to vaccinate people against malaria. Many scientists warn that this vaccination strategy violates one of the most basic human rights, informed consent, since neither the mosquitoes used as literal syringes nor the governments who use them are going to ask for consent.
The massive funding comes in part from leading vaccine proponent Bill Gates.
Gates has for several years advocated for using genetically altered mosquitoes to deliver vaccines. The Gates-backed Leiden University Medical Center in the Netherlands is testing such a vaccine for malaria using genetically modified mosquitoes.
McCullough cited a paper published in the New England Journal of Medicine (NEJM) in November reporting results from a double-blind, controlled clinical trial at two university medical centers in the Netherlands, which includes researchers from Leiden University.
The trial evaluated the safety, side effects and efficacy of immunizing people via mosquito bites, using mosquitoes infected with a genetically engineered version of the parasite that causes malaria.
Malaria is caused by plasmodium parasites, which spread to humans through bites from infected mosquitoes. Existing malaria vaccines have limited efficacy that lasts for only short periods of time.
Alternative strategies, which include the use of mosquitoes as a literal vaccine syringe, “may seem like a good idea,” Karl Jablonowski, Ph.D., senior research scientist at Children’s Health Defense, told The Defender. “Malaria commonly afflicts those in poorer countries with limited access to healthcare. If we could make a change to the environment that improves the lives of all and diminishes the lives of none, in theory that would be progress.”
“The problem,” he said, “is that every detail of it looks like a bad idea.”
The Dutch researchers had previously engineered the “GA1” version of the malaria-causing parasite to stop developing 24 hours after being introduced into the human body.
“Theoretically, these parasites wouldn’t cause malaria but would prime the immune system to recognize non-genetically modified pathogenic malarial parasites and trigger an immune response,” Dr. Brenda Baletti wrote for The Defender on Jan. 10.
GA1 showed poor efficacy.
The next version of the genetically modified parasite, GA2, halts development later — six days post-infection — when the parasite is replicating inside of human liver cells.
Jablonowski said this is not necessarily safe. The genetic modifications are intended to stop development in the liver stage before the parasite can proceed to the blood stage and become infective, he said. However, “The protozoa can still replicate, both sexually and asexually. This means the genetically modified protozoa can reproduce with wild-type to produce an infective genetically modified organism not bound by the original design.”
The study tested GA2 against GA1 and placebo in a small number of healthy adults ages 18 to 35. The genetically modified parasites were injected into the human subjects via mosquito bites.
In the first phase of the study, participants received either 15 or 50 bites from mosquitoes infected with GA2 to identify the highest dose without harmful side effects.
Next, researchers randomly assigned healthy adults who had not previously been infected with malaria to one of three groups. One was exposed to 50 bites from GA2, another to 50 bites from GA1, and the third to 50 bites from uninfected mosquitoes, the placebo group. There were nine participants in the GA2 group, eight in the GA1 group, and three in the placebo group.
The researchers completed three sessions of 50 bites per session — to simulate a three-dose vaccine regimen. Three weeks later, all test subjects were exposed to five bites from mosquitoes carrying non-genetically engineered malarial parasites.
Before being exposed to the non-genetically engineered parasites, the researchers reported that the subjects in both GA1 and GA2 groups had some anti-malarial antibodies. They found that GA2 provided greater efficacy (89%) against malaria and induced a higher immune response than either GA1 or placebo. They also said the vaccine was “safe” with no significant difference in adverse events within the groups.
Adverse events included skin redness and itchiness from the bites, which most participants experienced and treated with antihistamines or topical corticosteroids. Some also reported muscle aches and pains and headaches.
Two participants had elevated troponin T levels, which indicates heart damage, or even a heart attack. However, investigators assessed these incidents as unrelated to the vaccination. One participant also showed elevated liver-function tests that researchers said were related to the antihistamines.
“The authors took a lot of liberties in identifying adverse events they considered related and unrelated to the experiment,” Jablonowski said. ”When 40% of your trial group have abdominal pains, 45% have a headache, 50% have malaise and fatigue, and 60% have nausea and vomiting — these are not small relative numbers.”
Two weeks ago, the same Dutch researchers published additional results in Nature Medicine from a second trial with the same GA2 genetically engineered parasite. In this trial, they exposed 10 research subjects to a single, “one-dose regimen” of the parasite.
That means the trial participants were exposed to one 50-bite session by mosquitoes infected with GA2. They reported that after six weeks, nine of the 10 subjects showed no breakthrough infections. They called the results “promising” and again called for further studies.
McCullough believes “there should be a moratorium, a ban, on all mosquito vector research right now for human conditions. No Institutional Review Board would agree to, you know, mass populating, mass vaccinating a population without their consent with mosquitoes.”
There would also be serious problems with tracking the effects of the vaccines themselves. “There would be no control on the dose or the inoculum, as an example. There would be no control over recognizing side effects,” McCullough said.
Jablonowski noted that 14 of the 75 originally assessed participants were excluded for medical reasons. If such a vaccine were released, “not only would a person not have foreknowledge of vaccination, they wouldn’t have after-knowledge of it either. If a medical condition arose, they would have no idea if they were infected with the genetically modified protozoan.”

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  Leiden University Medical Center, Scientists sound alarm on Bill Gates-advocated use of mosquitoes to vaccinate humans, WorldTribune.com

Scientists sound alarm on Bill Gates-advocated use of mosquitoes to vaccinate humans

by WorldTribune Staff, January 13, 2025 Real World NewsDr. Peter McCullough noted in a recent post to his Substack.com blog: “It seems as if the world of vaccinology has ramped up to a feverish pitch with amplified research, massive funding, and no limit to the extent in which vaccines could be injected into humans.”
That amplified research now includes human clinical trials that use mosquitoes to vaccinate people against malaria. Many scientists warn that this vaccination strategy violates one of the most basic human rights, informed consent, since neither the mosquitoes used as literal syringes nor the governments who use them are going to ask for consent.
The massive funding comes in part from leading vaccine proponent Bill Gates.
Gates has for several years advocated for using genetically altered mosquitoes to deliver vaccines. The Gates-backed Leiden University Medical Center in the Netherlands is testing such a vaccine for malaria using genetically modified mosquitoes.
McCullough cited a paper published in the New England Journal of Medicine (NEJM) in November reporting results from a double-blind, controlled clinical trial at two university medical centers in the Netherlands, which includes researchers from Leiden University.
The trial evaluated the safety, side effects and efficacy of immunizing people via mosquito bites, using mosquitoes infected with a genetically engineered version of the parasite that causes malaria.
Malaria is caused by plasmodium parasites, which spread to humans through bites from infected mosquitoes. Existing malaria vaccines have limited efficacy that lasts for only short periods of time.
Alternative strategies, which include the use of mosquitoes as a literal vaccine syringe, “may seem like a good idea,” Karl Jablonowski, Ph.D., senior research scientist at Children’s Health Defense, told The Defender. “Malaria commonly afflicts those in poorer countries with limited access to healthcare. If we could make a change to the environment that improves the lives of all and diminishes the lives of none, in theory that would be progress.”
“The problem,” he said, “is that every detail of it looks like a bad idea.”
The Dutch researchers had previously engineered the “GA1” version of the malaria-causing parasite to stop developing 24 hours after being introduced into the human body.
“Theoretically, these parasites wouldn’t cause malaria but would prime the immune system to recognize non-genetically modified pathogenic malarial parasites and trigger an immune response,” Dr. Brenda Baletti wrote for The Defender on Jan. 10.
GA1 showed poor efficacy.
The next version of the genetically modified parasite, GA2, halts development later — six days post-infection — when the parasite is replicating inside of human liver cells.
Jablonowski said this is not necessarily safe. The genetic modifications are intended to stop development in the liver stage before the parasite can proceed to the blood stage and become infective, he said. However, “The protozoa can still replicate, both sexually and asexually. This means the genetically modified protozoa can reproduce with wild-type to produce an infective genetically modified organism not bound by the original design.”
The study tested GA2 against GA1 and placebo in a small number of healthy adults ages 18 to 35. The genetically modified parasites were injected into the human subjects via mosquito bites.
In the first phase of the study, participants received either 15 or 50 bites from mosquitoes infected with GA2 to identify the highest dose without harmful side effects.
Next, researchers randomly assigned healthy adults who had not previously been infected with malaria to one of three groups. One was exposed to 50 bites from GA2, another to 50 bites from GA1, and the third to 50 bites from uninfected mosquitoes, the placebo group. There were nine participants in the GA2 group, eight in the GA1 group, and three in the placebo group.
The researchers completed three sessions of 50 bites per session — to simulate a three-dose vaccine regimen. Three weeks later, all test subjects were exposed to five bites from mosquitoes carrying non-genetically engineered malarial parasites.
Before being exposed to the non-genetically engineered parasites, the researchers reported that the subjects in both GA1 and GA2 groups had some anti-malarial antibodies. They found that GA2 provided greater efficacy (89%) against malaria and induced a higher immune response than either GA1 or placebo. They also said the vaccine was “safe” with no significant difference in adverse events within the groups.
Adverse events included skin redness and itchiness from the bites, which most participants experienced and treated with antihistamines or topical corticosteroids. Some also reported muscle aches and pains and headaches.
Two participants had elevated troponin T levels, which indicates heart damage, or even a heart attack. However, investigators assessed these incidents as unrelated to the vaccination. One participant also showed elevated liver-function tests that researchers said were related to the antihistamines.
“The authors took a lot of liberties in identifying adverse events they considered related and unrelated to the experiment,” Jablonowski said. ”When 40% of your trial group have abdominal pains, 45% have a headache, 50% have malaise and fatigue, and 60% have nausea and vomiting — these are not small relative numbers.”
Two weeks ago, the same Dutch researchers published additional results in Nature Medicine from a second trial with the same GA2 genetically engineered parasite. In this trial, they exposed 10 research subjects to a single, “one-dose regimen” of the parasite.
That means the trial participants were exposed to one 50-bite session by mosquitoes infected with GA2. They reported that after six weeks, nine of the 10 subjects showed no breakthrough infections. They called the results “promising” and again called for further studies.
McCullough believes “there should be a moratorium, a ban, on all mosquito vector research right now for human conditions. No Institutional Review Board would agree to, you know, mass populating, mass vaccinating a population without their consent with mosquitoes.”
There would also be serious problems with tracking the effects of the vaccines themselves. “There would be no control on the dose or the inoculum, as an example. There would be no control over recognizing side effects,” McCullough said.
Jablonowski noted that 14 of the 75 originally assessed participants were excluded for medical reasons. If such a vaccine were released, “not only would a person not have foreknowledge of vaccination, they wouldn’t have after-knowledge of it either. If a medical condition arose, they would have no idea if they were infected with the genetically modified protozoan.”

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The American Free Press is Back!
  Leiden University Medical Center, Scientists sound alarm on Bill Gates-advocated use of mosquitoes to vaccinate humans, WorldTribune.com

Scientists reveal face of ‘completely unknown’ human ancestor that rewrites history of our evolution

By ELLYN LAPOINTE FOR DAILYMAIL.COM Published: 18:03 EST, 14 January 2025 | Updated: 18:18 EST, 14 January 2025

‘Digital Twins’ Are No Longer Science Fiction

’Digital Twins’ Are No Longer Science Fictionvar _comscore = _comscore || [];_comscore.push({ c1:”2″, c2:”6035286″, options: {enableFirstPartyCookie: true, bypassUserConsentRequirementFor1PCookie:true }});( function() {var s = document.createElement(“script”), el = document.getElementsByTagName(“script”)[0]; s.async = true; s.src = “https://sb.scorecardresearch.com/cs/6035286/beacon.js”; el.parentNode.insertBefore(s, el);})();SubscribeSign in

College Students Gain Holiday Muscle, Not Just Holiday Fat: The Science Behind Seasonal Fitness

With the turn of the calendar from December to January, many individuals across the United States find themselves grappling with the aftereffects of the holiday cheer—most prominently, a noticeable increase in their body weight. Research points out that, on average, Americans in their midlife and older years gain between one to one and a half pounds during the stretch of festivities from November through January. While such modest weight gain may not seem alarming at first glance, it is essential to recognize that even slight accumulations of fat can adversely affect long-term health. This incremental weight gain, often regarded as inconsequential, can build up over the years, leading to serious health concerns that permeate into later stages of life. In an intriguing twist, new research highlights a significant distinction between the holiday weight fluctuations observed in older adults compared to those of college students. Unlike their older counterparts, college students experience similar weight changes during the holiday season, but the composition of that weight is notably different. They are more likely to gain muscle rather than fat, signaling a variety of underlying physiological mechanisms at play during this pivotal life stage. The exploration of these differences was initiated by obesity researcher Martin Binks, who serves as the professor and chair of George Mason University’s Department of Nutrition and Food Studies. Dr. Binks expressed his surprise at these findings, acknowledging that they raise several critical questions regarding how life transition periods influence body composition and health. He emphasizes that understanding the context surrounding weight gain during holiday seasons is essential for delineating the varying impacts on health across different life stages. While older adults grapple with metabolic slowdowns and lifestyle factors that encourage fat accumulation, younger adults, especially those in college, tend to engage in more physically demanding activities that promote muscle gain. The conclusions drawn from this study could have wide-ranging implications for strategies aimed at tackling obesity. As college students experience a unique combination of academic stress, social events, and physical activity, identifying what drives their metabolic responses during the holiday period may provide new insights for addressing weight management during critical transition periods. The general trend of weight gain among older adults exacerbates the ongoing epidemics of obesity and related health issues, making it imperative to investigate potential protective factors present in the younger population. Dr. Binks, whose expertise spans over two decades in the realm of metabolic disease, has guided numerous patients in addressing weight challenges and enhancing quality of life. His commitment to mentorship and education is reflected in the recent publication, which emerged from research conducted by undergraduate students under the supervision of graduate peers and Binks himself. This collaborative approach underlines the significance of nurturing academic inquiries in impactful health-related subjects, ultimately aligning with the broader vision of enhancing nutritional understanding and practices. The pivotal study, entitled “Holiday Weight Change in a US College Student Sample: A Prospective Observational Cohort Study,” was recently published in the esteemed journal, Obesity Science & Practice. The January 2025 publication features additional contributions from an array of researchers across various prestigious universities such as Texas Tech University, the University of Cincinnati, Princeton University, and the University of Oregon. This collaborative effort demonstrates the vital role that academic partnerships play in advancing our collective understanding of public health issues. With each holiday season presenting unique dietary and social challenges, the distinction between how different age groups respond to these challenges poses essential considerations. The nuanced understanding of weight changes drawn from Binks’ research emphasizes the need for intervention strategies that cater to diverse demographics. Rather than imposing a one-size-fits-all approach to weight management, it is critical to differentiate the underlying mechanisms at play. Moreover, the findings may also shape future research initiatives designed to delve deeper into the biological and psychological aspects influencing weight gain and composition during and after the holiday season. The potential health implications of effective interventions that harness the distinct advantages of youth may inspire new methodologies in combating obesity and fostering healthier lifestyle habits among older adults. As Dr. Binks looks to the future, he is passionate about advancing studies that could further elucidate these intriguing differences in weight management across age groups. Understanding the variables that contribute to the dual pathways of muscle and fat gain during holidays can yield rich data that may inform public health recommendations, educational campaigns, and even clinical practices. Embracing this holistic understanding of weight dynamics during holiday periods will ultimately contribute to more effective long-term health outcomes. Furthermore, the interplay between social environments, dietary behaviors, and physical activities instigated by holiday festivities deserves deeper scrutiny. Recognizing that stress and celebration can provoke different responses in various individuals suggests a need to adopt a more personalized approach to nutritional acceptance and management. In conclusion, the divergence in weight gain patterns between college students and older adults during the holiday season offers a fascinating glimpse into the importance of life stages in shaping health outcomes. With continuous advancements in research, we can hope to uncover actionable insights that promote healthier living across age demographics, mitigating the risks associated with unwanted fat accumulation and chronic health conditions. Subject of Research: The differences in holiday weight gain between college students and older adults.Article Title: Holiday Weight Change in a US College Student Sample: A Prospective Observational Cohort Study.News Publication Date: January 8, 2025.Web References: DOI linkReferences: NoneImage Credits: None Keywords: Weight gain, Obesity, Nutrition, Public health, College students, Metabolic disorders.