From Bethesda Magazine: Science-inspired glass art

Nothing is off-limits to Jane Hartman, a scientist with multiple degrees and a stylized art business who creates glass renderings of E. coli bacteria, trilobites and more.

“I once made a tapeworm Christmas tree ornament,” the Rockville resident says. “Tapeworms are gross, but if you make it pretty colors, people say, ‘Oh, what’s that?’”

Jane Hartman holds a fused glass rendering of Staphylococcus (bacteria) that she made. She also crafted her earrings, which depict coronavirus. Photo credit: Lindsey Max

Through Trilobite Glassworks, her part-time business, Hartman, 67, designs fused and stained glass items that are both eye-catching and scientifically accurate. Her company’s name is a nod to her master’s degree in paleontology, in honor of the extinct creature called the trilobite. Whether it’s a tiny plate featuring the bacteria that causes gonorrhea, glass earrings displaying Staphylococcus aureus bacteria, or a norovirus fused-glass refrigerator magnet, the widowed mother of three adult children finesses the glass to bring Mother Nature’s beauty to life. 

“She clearly has this amazing intersection of art and science that she does so well,” says customer Krista Wigginton, a professor of civil and environmental engineering at the University of Michigan. “She understands the science, but she also makes beautiful art.” 

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For the past seven years, Wigginton has commissioned decorative plates from Hartman as a gift for each of her students when they defend their doctoral thesis. Glass renderings of viruses and double-stranded DNA genomes memorialize the students’ efforts. 

“We reach out to her when we have a defense coming up, and she’ll ask for two or three papers from the student to get an idea of the topic,” Wigginton says. “What’s clear is that she knows the science.”

In addition to her master’s degree in paleontology from the University of Wyoming, Hartman holds a bachelor’s degree in geology from the University of Michigan. After college, she married, started a family, and created glassware as a hobby. 

Hartman works out of a studio in the basement of her home, which contains soldering irons, two kilns, hundreds of sheets of glass, and about 100 jars of colorful crushed glass. When she started marketing her products in the early 2000s, Hartman crafted more traditional glass pieces, such as stained glass windows and suncatchers, in hopes of attracting a broader audience. When she named her business Trilobite Glassworks, it garnered questions from science fans asking if she created trilobites. In 2009, she bowed to the demand she saw for specialized scientific artwork. Hartman started taking commissions, as science-focused customers saw her talent. 

“That’s where I started doing really geeky, really neat stuff because scientists wanted art that depicted what they were researching,” she says. Now she has a constant waiting list.

Hartman’s art is available on her Etsy website, Trilobite Glassworks, and through trilobiteglassworks.weebly.com. Science lovers are drawn to her unique wares in the form of earrings, necklaces, dishes, paperweights or refrigerator magnets. She researches, designs and creates nearly 30 commissions a year, she says, in addition to offering smaller products.

Anne Estes teaches microbiology at Towson University and has been scooping up Hartman’s scientific masterpieces for years. In her classroom, Estes proudly dons necklaces with glass resembling E. coli, cyanobacteria and a bacterial stomach infection called Helicobacter pylori. 

“It was my reward for the first five or six times I taught my microbiology class; at the end of every semester, I allowed myself to buy one piece of Jane’s work,” Estes says. “People will go, ‘Oh, what a neat piece of glass.’ I’ll say, ‘It’s beautiful, but it’s really C. diff, which can kill you.’ ”

Catherine Linnen, from the University of Kentucky’s biology department, commissions bespoke glass pieces for her Ph.D. candidates. 

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“Every piece Jane has done for me has been really special and unique and beautiful,” she says. “The students and postdocs have absolutely loved them, and now it’s a known tradition.” 

Hartman concedes that her uncommon art is an acquired taste. “Non-scientists sometimes are like, ‘Wow, that’s really cool, but you’re weird, Jane,’ ” she says. “That’s funny and that’s OK—I take it as a compliment.” 

This appears in the March/April 2025 issue of  Bethesda Magazine.

Spanish and Swedish scientists develope simple blood test for early detection of Alzheimer’s disease

Thursday, 10 April 2025, 19:28

Joint research by Spanish and Swedish scientists has found a method that makes it possible to determine with very high reliability whether a person is suffering from Alzheimer’s at a very early stage, based on blood levels of a specific biomarker, the protein p-tau217. This is how the researchers, who have published the results of their work in the scientific journal Nature Medicine, summarise their findings.
This is an important clinical advance that opens the door to generalised screening by specialists for the early detection of Alzheimer’s disease in patients with symptoms of cognitive impairment, an early diagnosis that would be key to being able to apply existing palliative treatments, which will allow better management of the disease and an improvement in their quality of life.

Early diagnosis is essential in the treatment of a disease that already affects 800,000 Spaniards – it is the dementia with the highest mortality rate – and which each year sees higher numbers of diagnoses due, among other factors, to the ageing population. Until now, the existing early screening methods for this disease have been lumbar punctures or positron emission tomography (PET), which are more expensive, more traumatic for the patient and, in the case of PET, not available in all regions.

It is a simple, cheap and automated procedure that would allow widespread screening of suspected patients by specialists.

The authors of the finding are researchers from the Pasqual Maragall Foundation and Barcelona’s Hospital del Mar Research Institute, who have worked in coordination with colleagues from the Swedish universities of Gothenburg and Lund. They have managed to prove the 90 per cent accuracy in clinical trials which involved 1,767 people at the Barcelona hospital, the Swedish hospitals of Gothenburg and Malmö, the Italian hospital of Brescia and a Swedish primary care area.

Using an automated blood test, the researchers have been able to determine the levels at which the presence of the p-tau217 protein can be used to determine whether a person will develop the disease or not. They have been able to establish two cut-off points according to the level of presence of the biomarker. If the test says that the level is below the low cut-off point, the result is negative. If it is above the high point, it is positive.
If it is somewhere in between, the risk exists and the diagnosis should be confirmed or ruled out with a lumbar puncture or a PET scan. However, Marc Suárez-Calvet, one of the authors of the study, stresses that “the results of this biomarker must always be interpreted by a neurologist or other specialised health professional, after a proper neurological assessment and never as an isolated test”.

In any laboratory

The Spanish scientific team highlights the clear possibility they see of implementing their method as the standard form of reliable early detection of Alzheimer’s disease in Spanish clinical practice. They say that the test is simple and very easy to use, as it can be performed “in any clinical laboratory”, which opens the door to widespread use and “more equitable access to care and better treatment”.
The analysis is 60-80 per cent cheaper than existing methods. The researchers believe that the test’s “low economic impact, coupled with its large-scale applicability, can contribute to improving access to early diagnosis of Alzheimer’s and to improving the clinical approach to the disease”.

Spanish and Swedish scientists develope simple blood test for early detection of Alzheimer’s disease

Thursday, 10 April 2025, 19:28

Joint research by Spanish and Swedish scientists has found a method that makes it possible to determine with very high reliability whether a person is suffering from Alzheimer’s at a very early stage, based on blood levels of a specific biomarker, the protein p-tau217. This is how the researchers, who have published the results of their work in the scientific journal Nature Medicine, summarise their findings.
This is an important clinical advance that opens the door to generalised screening by specialists for the early detection of Alzheimer’s disease in patients with symptoms of cognitive impairment, an early diagnosis that would be key to being able to apply existing palliative treatments, which will allow better management of the disease and an improvement in their quality of life.

Early diagnosis is essential in the treatment of a disease that already affects 800,000 Spaniards – it is the dementia with the highest mortality rate – and which each year sees higher numbers of diagnoses due, among other factors, to the ageing population. Until now, the existing early screening methods for this disease have been lumbar punctures or positron emission tomography (PET), which are more expensive, more traumatic for the patient and, in the case of PET, not available in all regions.

It is a simple, cheap and automated procedure that would allow widespread screening of suspected patients by specialists.

The authors of the finding are researchers from the Pasqual Maragall Foundation and Barcelona’s Hospital del Mar Research Institute, who have worked in coordination with colleagues from the Swedish universities of Gothenburg and Lund. They have managed to prove the 90 per cent accuracy in clinical trials which involved 1,767 people at the Barcelona hospital, the Swedish hospitals of Gothenburg and Malmö, the Italian hospital of Brescia and a Swedish primary care area.

Using an automated blood test, the researchers have been able to determine the levels at which the presence of the p-tau217 protein can be used to determine whether a person will develop the disease or not. They have been able to establish two cut-off points according to the level of presence of the biomarker. If the test says that the level is below the low cut-off point, the result is negative. If it is above the high point, it is positive.
If it is somewhere in between, the risk exists and the diagnosis should be confirmed or ruled out with a lumbar puncture or a PET scan. However, Marc Suárez-Calvet, one of the authors of the study, stresses that “the results of this biomarker must always be interpreted by a neurologist or other specialised health professional, after a proper neurological assessment and never as an isolated test”.

In any laboratory

The Spanish scientific team highlights the clear possibility they see of implementing their method as the standard form of reliable early detection of Alzheimer’s disease in Spanish clinical practice. They say that the test is simple and very easy to use, as it can be performed “in any clinical laboratory”, which opens the door to widespread use and “more equitable access to care and better treatment”.
The analysis is 60-80 per cent cheaper than existing methods. The researchers believe that the test’s “low economic impact, coupled with its large-scale applicability, can contribute to improving access to early diagnosis of Alzheimer’s and to improving the clinical approach to the disease”.

Movie Theaters Issue Warnings After Outbreak of Insane ‘A Minecraft Movie’ TikTok Trend

Movie theaters have issued a warning that “disruptive behavior” will “not be tolerated” after an insane “A Minecraft Movie,” viral TikTok trend encouraged young audiences to go throw food, scream, and more. Advertisement One warning posted at a Cineworld movie house in the United Kingdom read: “Any form of anti-social behavior, especially anything that may…

5 Cybersecurity Measures Every Business Should Implement

Cybersecurity is more important than ever for businesses of all sizes. A data breach can lead to loss of sensitive customer information, financial losses, and damage to your company’s reputation. Implementing proactive cybersecurity measures can help safeguard your business against cyber threats. Here are five crucial cybersecurity measures every business should put in place.

Perform Risk Assessments

The first step is to conduct cyber risk assessments regularly. This allows you to identify your company’s vulnerabilities, threats, and potential impacts of a cyberattack. A risk assessment examines your technology infrastructure, policies, employee training, data storage and transmission, and incident response readiness. Knowing your risks enables you to focus security efforts on the most problematic areas. Risk assessments also highlight improvements so you can bolster defenses. Conduct assessments frequently to account for your evolving business needs.
      2. Install Firewalls and Anti-Malware Software
Firewalls and anti-malware programs provide vital protection against cyber threats. Firewalls control network access while anti-malware software scans for and eliminates viruses, spyware, ransomware, and other malicious code. Firewalls and anti-malware tools should be deployed across networks, systems, and endpoints. Make sure solutions are configured properly and kept updated with the latest patches. Out-of-date software leaves openings for adversaries. Use advanced AI and machine learning-driven cybersecurity tools whenever possible.
      3. Implement Access Controls
Limiting access to data and networks reduces exposure. The principle of least privilege should be used; employees and systems should only have permissions required for their specific role. Multifactor authentication adds another layer of security by requiring multiple forms of identity verification before granting access. Encryption also helps control access to information. With encryption, data is scrambled into coded form so that only authorized parties can decipher and consume the content. Log and monitor access to quickly spot any unusual activity.
      4. Provide Cybersecurity Training
Ongoing cybersecurity education ensures employees are prepared to identify and respond to threats. Training should teach best practices for passwords, handling sensitive data, identifying phishing attempts, using company devices securely, and reporting suspicious activity. Employees are your first line of defense. Equipping staff with cyber skills empowers them to make smart security decisions. Avoid complacency by conducting drills and refresher courses regularly. Make training engaging and relevant to resonate with personnel.
      5. Perform Penetration Testing
Penetration testing, also known as pentesting, involves hiring ethical hackers to safely simulate cyberattacks against your systems and networks. Skilled security professionals use tools and techniques similar to real-world hackers. The goal is to exploit vulnerabilities and gain access, enabling you to find and resolve security gaps before criminals can take advantage of them. Pentesting provides insights you can’t get any other way and is one of the most effective ways to assess and bolster cyber defenses. Conduct tests on a regular basis to keep up with evolving threats.
Strong cybersecurity is a necessity for modern enterprises. Implementing these strategies greatly improves resilience. Staying vigilant and continuously refining cyber defenses will help safeguard your business-critical systems and data from constantly evolving online threats. Protecting your assets in today’s interconnected world requires earnest commitment to cybersecurity best practices. Make cybersecurity central to your overall business strategy.

Cox Business partners with RingCentral to bring AI-powered voice, chat, video and contact center capabilities to California Customers

Cox Business, a leading provider of advanced cloud, managed IT and fiber-based network solutions, is the commercial division of Cox Communications.The company is constantly evolving its product portfolio to drive greater outcomes for customers, including a new partnership with RingCentral, Inc. (NYSE: RNG), a leading global provider of AI-powered trusted communications.
“Technology needs and trends, including telephony, are ever-changing.” said Cox Business California Vice President Jodi Duva. “Our partnership with RingCentral provides innovative and malleable communications solutions for commercial clients who need to streamline organizational operations, boost employee productivity, deliver exceptional customer experiences, and initiate long-term growth.”
RingCentral’s AI-first, cloud-based contact center solution is one of several advanced tools Cox Business offers its California customers including healthcare providers, K-12 and higher education, financial institutions, and federal, state and local government organizations.
In addition to fiber-powered internet connections, voice and video services, Cox Business offers specialized solutions and leading customer care and IT support through separate divisions that support the unique connected environments and hospitality experiences in California, including:
RapidScale, available nationwide regardless of internet provider, offers comprehensive managed IT and cloud services, including public cloud migration and management.
Hospitality Network enables smart technology and integration services for hotels, convention centers, stadiums and arenas, including Snapdragon Stadium and Frontwave Arena in San Diego and Honda Center in Orange County.
Blueprint RF serves hotels, multi-dwelling units and more with customized Wi-Fi networks and solutions, designed to enhance the guest and resident experience.
Cox Private Networks specializes in solving specific connectivity challenges beyond traditional networks
“Cox has been a part of major California communities including San Diego, Irvine, Palos Verdes, and Santa Barbara for decades and we’re proud to offer innovative, forward-focused solutions for businesses at every level,” said Duva. “More importantly, Cox is a committed community partner with a strong record of charitable giving, volunteerism, support of local nonprofits, sustainability initiatives and digital equity.”

Originally Published: April 10, 2025 at 1:33 PM PDT

Pravinkoodu Shappu out on OTT a day earlier: Where to watch Basil Joseph’s film

Basil Joseph’s latest mystery thriller, Pravinkoodu Shappu, has made its much-awaited OTT premiere on SonyLiv and OTTplay Premium. The Malayalam film, which also features Soubin Shahir and Chemban Vinod Jose in key roles, has dropped in the digital space a day earlier than announced. Here’s more about Basil Joseph’s film, which delves into a murder mystery. Pravinkoodu Shappu out on OTTplay Premium Pravinkoodu Shappu, starring Basil Joseph in the lead role as a cop, released in theatres on January 16, 2025. Now, nearly two months later, the Sreeraj Sreenivasan directorial has premiered on SonyLiv and OTTplay Premium. Interestingly, Pravinkoodu Shappu was made available for streaming on April 10, 2025, though the OTT platform had announced that it would be available from April 11.  
A poster of Pravinkoodu ShappuSonyLiv seems to be following this practice of ‘early release’, at least in the case of Malayalam movies. Unni Mukundan-starrer Marco, Joju George’s Pani and Asif Ali’s hit film Rekhachithram were the other recent Malayalam films that landed on the eve of the scheduled dates for OTT release. But hey, no one is complaining. Fans are just happy that they will get to see Basil Joseph’s film one day in advance. Non-Malayalam speakers have the option to watch Pravinkoodu Shappu in Hindi, Tamil, Telugu and Kannada with English subtitles. Basil Joseph’s film delves into a murder mystery. After a toddy shop owner is found dead, CI Santhosh is tasked with probing the case, which has 11 suspects.
Other recent Malayalam films on OTT Rekhachithram stars Asif Ali, Anaswara RajanOther recent Malayalam films to premiere on OTTplay Premium include Rekhachithram, which starred Asif Ali and Anaswara Rajan. The film, which is also a mystery thriller, follows cop Vivek, who unearths a skeleton and sets out to probe a 40-year-old murder case. His probe takes him to a film set in 1985. Even while probing a murder mystery, Rekhachithram is a beautiful film that pays homage to Malayalam cinema.  
Another recent Malayalam film to land on SonyLiv and OTTplay Premium is Marco, a brutal actioner. Malayalam’s most violent film, directed by Haneef Adeni, also featured Siddique, Jagadish, and Kabir Duhan Singh in other key roles.

Jack box office collection day 1-Siddhu Jonnalagadda’s film takes a dismal start

Jack is Siddhu Jonnalagadda’s new film that hit the screens on April 10, 2025. Word of mouth has been mixed, as the action comedy has taken a dull start at the box office. Post the success of DJ Tillu, Siddhu Jonnalagadda became a massive star, and everyone was eager to see how much Jack made at the box office on day one. Well, the numbers are here, and as per the latest update, Jack has made around Rs 4 crore gross on day one of its release.Siddhu Jonnalagadda Jack day one collectionsThis is a disappointing number considering Siddhu’s recent craze and the business of his last film, Tillu Square. The net collection of the film will be somewhere around Rs 2.5 crore, and with such dull word of mouth, Jack will surely falter at the box office in the next few days.The occupancy of Jack was around 80% in the morning shows, and it picked up in the afternoon shows. But ever since the talks have come out, the occupancy has dropped big time during the evening and night shows.The sad part is that the other release, Good Bad Ugly, featuring Ajith, has opened better than Jack. As the film is filled with fan moments, the occupancy for GBU is a bit better in the evening and night shows on day one.Jack day one collectionsBommarillu Bhaskar has directed the film, and he has disappointed everyone once again with his silly narration. Jack is a spy thriller with a dose of comedy. But the comedy executed by Siddhu Jonnalagadda has failed to evoke humor. Nothing has worked for the fans or the general audience, and this has disappointed the Krishna and His Leela star.Jack OTT platform detailsJack has been produced by veteran BVSN Prasad, and he has spent a decent amount on the film. As the long weekend is on, the makers would want the film to make some money at the box office. Jack’s OTT rights have been sold to Netflix for a solid amount, and the makers would surely land in the profit zone thanks to this deal.Siddhu JonnalagaddaIn the US too, Jack has opened to a very disappointing note. Vaishnavi Chaitanya, who made a solid debut with Baby, plays the female lead in this film, and she too is being trolled for her performance and dull screen presence. So, in the days to come, we need to see how much Jack will make at the box office.