Penn Vet professor Andrew Modzelewski named 2024 Packard Fellow for Science and Engineering

Andrew Modzelewski, assistant professor in the Department of Biomedical Sciences at the University of Pennsylvania’s School of Veterinary Medicine, was named a 2024 Packard Fellow for Science and Engineering for his research in ancient viruses and mobile elements known as retrotransposons.

Since 1988, the David and Lucile Packard Foundation has selected 20 scientists each year from 50 invited institutions across the nation to receive flexible funding for science and engineering exploration. As a 2024 Packard Fellow, Modzelewski will receive $875,000 in individual grant funding distributed over five years to advance his research. 

“This extraordinary class of Fellows joins the community of Packard Fellows who are pushing the boundaries of innovation and discovery to contribute to science and engineering in ways that make a real difference to our world,” Richard Alley, chair of the Packard Fellowships for Science and Engineering Advisory Panel, said in the announcement. 

Modzelewski was recognized for his work in retrotransposons, which make up nearly 50% of the human genome. Retrotransposons are mobile elements that can move within a host genome and are especially important in embryonic development. 

Through genome editing techniques, live cell imaging, and sequencing techniques, Modelewski’s research lab studies the behavior of retrotransposons and how they contribute to embryonic development, disease progression, and regenerative medicine. 

“The freedom and flexibility provided by this fellowship will support new avenues of research that could lead to significant advancements in our understanding of genetics and health,” Modzelewski said in the Penn Vet announcement. 

Modzelewski’s research could also contribute to understanding the connections between aging and cancer.

“His innovative research on retrotransposons in early embryonic development not only advances scientific knowledge but also exemplifies the spirit of discovery that defines Penn Vet,” Christopher Lengner, chair of the Department of Biomedical Sciences and Harriet Ellison Woodward Professor of Biomedical Science, said.