The Prime Minister says he wants the significant increase in defence spending by his government to translate into job opportunities for businesses in Merseyside. Sir Keir Starmer was at the Cammell Laird shipyard in Wirral on Thursday, where he met staff and assured them of their crucial role in the country’s defence plans. Last week,…
Details
March 6, 2025 Ken & Robin Roth with Stacy & Troy Lyscio On February 1, 2025, the Arizona Science Center transformed into a feast for the senses as they hosted the annual ‘Galaxy Gala’ and unveiled the marvelous debut of its eclectic Power of Poison exhibit, which continues the Center’s tradition of educating, inspiring and…
Details
Texas Spring Break Travel Alert: New Last-Minute Deals at Five Jellystone Park Camp-Resorts – Travel Industry Today – EIN Presswire
Details
The event, held from March 4 to 6 at the Berlin Exhibition Centre, is under the theme “The World of Travel Lives Here.” SCTDA participation aims to highlight Sharjah’s unique tourist attractions, solidifying its position on the global tourism map.Interactive pavilion showcasing Sharjah’s attractions
At the exhibition, Sharjah’s distinguished pavilion offers visitors an interactive journey to explore the emirate’s natural, cultural, and recreational destinations, including desert, mountainous, and coastal areas, heritage sites, and modern landmarks. This immersive experience showcases the exceptional tourism offerings of the emirate.
Sharjah’s position as a prominent tourist destination
His Excellency Khalid Jasim Al Midfa, Chairman of the Sharjah Commerce and Tourism Development Authority, emphasised the exhibition’s importance in presenting Sharjah’s diverse landmarks, rich culture, and advanced infrastructure. He highlighted the strong historical relations between Sharjah and Europe, particularly Germany, positioning the emirate as a prime destination for European and German tourists seeking unique cultural experiences.
Participants and collaborative approach to tourism development
The Sharjah delegation includes representatives from key government entities such as the Environment and Protected Areas Authority, Sharjah International Airport Authority, and Sharjah Museums Authority, alongside private sector participants including Air Arabia and Sharjah National Hotels. The collaborative approach reflects Sharjah’s commitment to developing its tourism and travel sectors.
Ongoing efforts in sustainable and cultural tourism
During the event, the Sharjah delegation will also showcase the emirate’s efforts in sustainable tourism, ecotourism, adventure tourism, and cultural tourism, which have enhanced Sharjah’s position as a regional tourism leader. The pavilion emphasises initiatives aimed at preserving cultural and environmental heritage while offering world-class tourism experiences.
Increased tourism from Europe and Germany
Sharjah’s participation in ITB Berlin 2025 is a significant opportunity to attract more visitors from Europe and beyond. The emirate has seen a notable increase in German hotel guests, with around 13,000 German visitors in 2023 and expectations for a rise to 14,000 in 2024. The number of European tourists is also growing, with a 16% increase in 2024, reflecting Sharjah’s growing appeal to international travelers.
Piers Morgan skewered Democratic lawmakers Thursday over their “pathetic” behavior during President Donald Trump’s address to Congress. The Democrats protested Trump’s speech in the House chamber Tuesday night and refused to applaud his special guests, with one congressman even getting escorted out for shouting at the president as he spoke. Morgan said on “Fox &…
Details
Just 6 kilometers (about 4 miles) of briny water separate the ocean’s surface from the depths known as the hadal zone. Yet for as much as we know what lurks in its cold darkness, it might as well be another world.
Details
Economic Club of Las Vegas to Host “Las Vegas’ Tourism Economy” Quarterly Luncheon – Travel Industry Today – EIN Presswire
Details
March 06, 2025
4 min read
Add topic to email alerts
Receive an email when new articles are posted on
Please provide your email address to receive an email when new articles are posted on .
Subscribe
Added to email alerts
We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Back to Healio
Key takeaways:There is only one mechanical heart pump available in the U.S. for patients with heart failure requiring left ventricular assistance. If the INNOVATE trial is successful, a second option could emerge. Left ventricular assist devices, which are mechanical heart pumps, are an important treatment for patients with advanced heart failure.LVADs assist weakened left ventricles to enable the heart to pump blood properly, and can be used as permanent solutions to the heart failure condition or used to stabilize a patient’s heart failure condition as a bridge to transplantation. LVADs are complex mechanical machines, and older past designs had problems with reliability and performance. In 2021, Medtronic halted the sale and distribution of its LVAD (HeartWare HVAD) due to the frequency of neurological adverse events and mortality compared with other devices, and prior to that, had issued a separate recall based on complaints that the internal pump may delay or fail to restart. That left only one LVAD on the U.S. market, the HeartMate 3 (Abbott), which has itself been subject to recalls that have required design modifications to address certain problems.
Sensing a need for a second LVAD option, researchers have begun the INNOVATE clinical trial comparing a new LVAD, the BrioVAD (BrioHealth Solutions), to the HeartMate 3. The primary outcome of the study will assess patient survival on the LVAD free of debilitating stroke or recovery of native heart function or receipt of a heart transplant up to 24 months following LVAD implant. Healio spoke with Francis D. Pagani, MD, PhD, national lead investigator for the INNOVATE trial and cardiac surgeon at the University of Michigan Health Frankel Cardiovascular Center, about why a new device is needed, why LVADs are so challenging, how the new device works and how patients with advanced HF might benefit if the trial is successful. Healio: Why is there a need for a new LVAD for patients with heart failure? Pagani: No. 1, the current technology we are using now has been in clinical use for 10 years. There’s a need to improve upon existing technology. No. 2, this is complex technology, and having only one pump available in the United States, if something should happen to this device, whether it’s a recall or supply-chain issues that make building the device problematic, there is no other option. For complex devices like this, there should always be more than just one option, for the safety of patients and to promote more technology development in the field. Healio: The HeartMate devices have had issues leading to recall and the HeartWare devices ended up being pulled from the market. Why have LVADs been so challenging in this way? Pagani: They are challenging. Think about what we are asking the device to do. We are trying to build a pump that replicates the function of the heart, to last an indefinite period of time. A lot needs to go into that design and development. We are asking a pump to function as the heart, and to be as reliable as the heart, and to not have any of the issues a normal heart would have. To replicate that kind of biological function is very complex. The devices we have now are exceedingly good. They do a fantastic job of achieving some of those excellent outcomes we are seeing. But there is still lots of room for improvement. Healio: How does the BrioVAD work compared with other mechanical heart pumps? Pagani: The BrioVAD has similar technology to the HeartMate 3. There are a few features on the BrioVAD that I think make it a very interesting pump. One is that it’s smaller in size. That is potentially very good, because it means the device might be available for patients with small body size or, in the future, it could potentially be tested in children, which is not possible for larger devices. Also important is that the percutaneously implanted driveline, which connects the pump to the outside world and the power supply, is much smaller and more flexible, and we think there may be benefit for patients in terms of reducing risk for infection and making it more comfortable for the patient. Healio: What is the heart failure community hoping to learn from this trial? Pagani: There are a number of things. Foremost is that we want to test the reliability and safety of the BrioVAD compared with HeartMate 3, which has established an excellent benchmark and achieved the best outcomes in the field over the past 30 years. So we are hoping that the BrioVAD meets or exceeds those benchmarks in terms of patient outcomes. We are also focusing on learning more about patient management. Are there things that we could do as physicians in the care of these patients to improve their outcomes? So we are testing the device itself and also trying to find ways to improve care for these patients. Healio: What are the implications if this trial is successful? Pagani: I think it will spur competition. If one company has a good device, another company will want to make a better device. I think it would create a competition that ultimately brings newer technology to the market, which is very good for the field, and everybody benefits by that. Hopefully, it will spur more interest in developing these types of heart pumps. As mentioned earlier, development of these devices is very challenging. There needs to be a lot of people involved from all different fields to develop these devices. Healio: Is there anything else you would like to mention? Pagani: The most important thing is that we need to increase choices for patients and physicians. To secure a safer environment for patients, we need different types of pumps in the field, and that is what we are working toward. References:
Published by:
Sources/DisclosuresCollapse
Source:
Healio Interviews
Disclosures:
Pagani reports that the University of Michigan does contract research with BrioHealth Solutions as part of being a center involved in the trial, but he receives no personal financial compensation.
Read more about
Add topic to email alerts
Receive an email when new articles are posted on
Please provide your email address to receive an email when new articles are posted on .
Subscribe
Added to email alerts
We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Back to Healio
Details
“People who grow up on islands think differently than people who grow up on continents.”So begins a parable featured in Navigating Our Way to Solutions in Marine Conservation, a new book edited by Larry Crowder, a professor of oceans at the Stanford Doerr School of Sustainability.The parable describes how island peoples have learned over millennia to sustain limited resources by considering local land and waters as one system. Cultivated over generations, islanders’ holistic approach to stewarding the natural world – from mountain summits to the sea and the human communities therein – imparts many lessons for modern marine conservation.“Historically, the field has been dominated by scholars who have led from a science-driven, disciplinary perspective,” said Crowder, whose first book on marine conservation was published 20 years ago. “We’ve learned that insights from rigorous scientific research are necessary, but not sufficient, for solving marine conservation challenges in the real world.”Published in Feb. 2025, the book showcases a wide range of approaches and expertise in modern ocean scholarship, with chapters written by nearly 50 co-authors from around the globe. Chapters discuss how to bridge the natural and social sciences, ways in which Western and Indigenous knowledge systems can complement one another, and stories of how academic insights can inform and support community governance.“The book celebrates the variety of voices and disciplines that can take us forward,” said Crowder, the Edward Ricketts Provostial Professor. Below, several co-authors share their thoughts on the future of marine conservation. Their chapters and the entire book can be read online for free through Open Book Publishers.Xavier Basurto is a professor of environmental social sciences at the Stanford Doerr School of Sustainability where he studies self-organization, particularly how small-scale fishers and other communities prioritize the future and environmental preservation ahead of short-term personal gain.Collin Closek is a marine scientist at the Center for Ocean Solutions in the Stanford Woods Institute for the Environment. Closek applies and optimizes molecular and computational tools to answer questions about marine ecology.Andrea Reid is an assistant professor at the University of British Columbia where she leads the Centre for Indigenous Fisheries. She is a citizen of the Nisg̱a’a Nation and a Canada Research Chair in Indigenous Fisheries Science.
Details
Extreme weather 2024 marked a historic year of climate extremes, becoming the first calendar year on record to exceed pre-industrial temperatures by 1.5°C. The United States also experienced 27 separate billion-dollar weather and climate disasters, resulting in 568 fatalities and $182.7 billion in damages — the fourth-costliest year on record. These devastating impacts, from Hurricane Helene’s unprecedented…
Details